The Effect of Anesthesia Type on Pulmonary Function

Anesthesia Clinical Trial

Official title:

The Effect of General or Spinal Anesthesia on Pulmonary Function Tests in Geriatric Patients

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT03399201
• Other study ID #: Spiro
• Status: Completed
• Phase: N/A
• Start date: February 16, 2018
• Est. completion date: December 2, 2018

Study information

• Verified date: December 2018
• Source: Tokat Gaziosmanpasa University
• Contact: n/a
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

The role of neuraxial anesthesia in preventing respiratory complications is a controversial in elderly patients. The aim of the study was to evaluate the benefits of neuraxial anesthesia on pulmonary function during post-operative term in geriatric patients undergoing to elective non-abdominal surgery.

Description:

Sixty elder patients will be randomly assigned to General anesthesia or Neuraxial anesthesia groups. Spirometry, will be performed at pre-operative and post-operative terms. Pulmonary function tests will be evaluated.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 60
• Est. completion date: December 2, 2018
• Est. primary completion date: December 2, 2018
• Accepts healthy volunteers: No
• Gender: All
• Age group: 65 Years to 95 Years

Eligibility

Inclusion Criteria:

• 65 years of age

• Undergoing non-abdominal surgery under anesthesia in supine position

Exclusion Criteria:

• Pulmonary disease

• Hematological disease

• Undergoing Abdominal surgery

• Non-supine position during surgery

• Nicotine Abuse

Related Conditions & MeSH terms

• Anesthesia
• Geriatric Patients

Intervention

Procedure:
• General anesthesia
induction with the intravenous anesthetic (Propofol) and maintenance with the inhalational anesthetic (Sevoflurane)
• Neuraxial anesthesia
Spinal anesthesia will be applied via the local anesthetic ( Bupivacaine).

Diagnostic Test:
• Spirometer
Pulmonary function will be evaluated via the portable spirometer (MIR Spirodoc, Spirodoc®, Roma, Italy)

Locations

Country	Name	City	State
Turkey	Gaziosmanpasa University Hospital	Tokat	Merkez

Sponsors (1)

Lead Sponsor	Collaborator
Tokat Gaziosmanpasa University

Country where clinical trial is conducted

Turkey, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	The changes on forced vital capacity	Forced vital capacity will be measured via spirometer	At Preoperative, postoperative 2. hours, postoperative 24. hours
Primary	The changes on forced expiratory volume in 1 s	Forced expiratory volume in 1 s will be measured via spirometer	At Preoperative, postoperative 2. hours, postoperative 24. hours
Primary	The changes on mid-expiratory flow (MEF 25-75)	mid-expiratory flow (MEF 25-75) will be measured via spirometer	At Preoperative, postoperative 2. hours, postoperative 24. hours
Primary	The changes on peak expiratory flow (PEF)	Peak expiratory flow (PEF) will be measured by the spirometer	At Preoperative, postoperative 2. hours, postoperative 24. hours