Anesthesia Clinical Trial
Official title:
Observational Study of the Effect of Tracheal Intubation and Tracheal Tube Position on Regional Lung Ventilation During General Anaesthesia
During any general anaesthetic which involves muscle relaxation artificial breathing is
required. This is most commonly provided by pushing air under pressure (positive pressure
ventilation) into the lungs via a tube in the airway (the tracheal tube). It has been
observed for many years that with this form of breathing the distribution of gas within the
lungs differs from that seen during 'natural' breathing: more of the gas goes to the upper
parts of the lung than lower parts. This change in how the gas is distributed can lead to
problems with how well oxygen is taken up by blood and carbon dioxide removed from the body.
Previous work using mathematical modelling has found that the position of the tracheal tube
might affect air distribution, but this has previously been difficult to study in 'real
life', requiring the use of radioactive dyes and computerised tomography (CT). However a
bedside test is now available which allows us to study these changes rapidly and
non-invasively, using electrical impedance tomography (EIT). The EIT device is commercially
available (PulmoVista®, Draeger UK) and is used in hospitals worldwide as a bedside monitor
of lung ventilation.
This study aims to investigate the effect of tracheal intubation on regional ventilation of
the lungs by comparing measurements before and after the patient is anaesthetised and
intubated. The investgiators aim to show whether altered patterns of ventilation are caused
by patients simply being asleep and ventilated, or whether these changes are due to the use
of a tracheal tube itself. The exact effect of tube position will also be studied by
measuring ventilation as the tube is deliberately advanced until it enters one of the lungs.
This will give us information about the ideal position for a tube within the trachea to
promote optimal ventilation patterns within the lungs
n/a
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