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Clinical Trial Summary

Prospective association study to analyse perioperative patients' outcome. Outcome comprises intraoperative and postoperative complications e.g. cardio-vascular events, allergic reactions, Possible variables which might have on influence: patient- and surgery-related data, patients' genetic background etc.


Clinical Trial Description

Background Anesthesia and surgery are related to unwanted adverse events, side effects and postoperative discomfort. Whereas severe complications like cardiovascular events are rare, postoperative side effects like nausea and vomiting, pain, long-lasting pain and pain related interference of daily activities are frequent. The question arises which patient is at specific risk for this sequelae. Pre-exiting predisposing factors (e.g. patients' genetic background), surgery and anesthesia related variables (drugs, techniques administered for anesthesia and analgesia) as well as psychological and social factors might influence the outcome. In this prospective association study these variables will be investigated in a well-described patient cohort presenting for elective surgery. Objective The aim of this study is to associate perioperative and postoperative complications and side effects as well as long-term outcome after surgery to patient- and surgery-related variables, including genetic variants. Methods Prospective association study performed in two independent patient cohorts. ;


Study Design


Related Conditions & MeSH terms


NCT number NCT02124499
Study type Observational
Source Insel Gruppe AG, University Hospital Bern
Contact Ulrike M Stamer, Prof. MD
Phone 0041-316329995
Email ulrike.stamer@dbmr.unibe.ch
Status Recruiting
Phase
Start date January 2011
Completion date June 2026

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