Preconditioning Volatile Anesthesia in Liver Surgery

Anesthesia Clinical Trial

Official title:

Preconditioning is Indeed Protective

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT01021228
• Other study ID #: StV 18-2008
• Status: Completed
• Phase: N/A
• First received: November 25, 2009
• Last updated: November 25, 2009
• Start date: August 2008
• Est. completion date: October 2009

Study information

• Verified date: November 2009
• Source: University of Zurich
• Contact: n/a
• Is FDA regulated: No
• Health authority: Switzerland: Ethikkommission
• Study type: Observational

Clinical Trial Summary

The purpose of this study is to compare the impact and outcome of continuous volatile anesthesia to continuous intravenous anesthesia and to preconditioning volatile anesthesia in liver surgery.

Description:

Comparing the impact and outcome of continuous volatile anesthesia to continuous intravenous anesthesia and to preconditioning volatile anesthesia in liver surgery.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 257
• Est. completion date: October 2009
• Est. primary completion date: October 2009
• Accepts healthy volunteers: No
• Gender: Both
• Age group: 18 Years to 90 Years

Eligibility

Inclusion Criteria:

• > 18 years

• benign and malign disease

• any type of liver surgery

• inflow occlusion during the liver surgery

Exclusion Criteria:

• < 18 years

• participation on other interventional and treatment randomized controlled trials,

• trauma of the liver

• liver cirrhosis

Study Design

Observational Model: Cohort, Time Perspective: Retrospective

Related Conditions & MeSH terms

• Anesthesia

Locations

Country	Name	City	State
Switzerland	Universtiy Hospital of Zurich, Department of Visceral and Transplantation Surgery	Zurich

Sponsors (1)

Lead Sponsor	Collaborator
University of Zurich

Country where clinical trial is conducted

Switzerland, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	peak ALT and AST levels representing the ischemia-reperfusion injury		post-operative	Yes
Secondary	length of hospital stay, length of ICU stay, blood loss and morbidity (post-operative complications)		post-operative	Yes