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Anesthesia clinical trials

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NCT ID: NCT04779528 Completed - Anesthesia Clinical Trials

Awake Nasal Fiber-optic Intubation of Severely Obese Patients in Lateral Position

Start date: March 1, 2021
Phase: N/A
Study type: Interventional

Airway management in severely obese patients remains a challenging issue for anesthetists and may lead to life-threatening situations. Awake Fiber-Optic Bronchoscopy Intubation (FOBI) technique is considered as the gold standard when a difficult airway is anticipated to secure the airway and to facilitate the surgery. FOBI is usually done in supine position, while (in conscious patients) lateral position is the most recommended position to keep the upper airway patent. This prospective clinical trial study will test whether awake FOBI in Lateral position will provide a safe profile or a significant advantage over FOBI in supine position, in morbidly obese patients undergoing elective bariatric surgery.

NCT ID: NCT04770259 Completed - Surgery Clinical Trials

Pre-surgical Protocol for Frail Elderly People in Order to Reduce Hospitalization Days (APOPM).

APOPM
Start date: May 30, 2021
Phase: N/A
Study type: Interventional

Elderly people (EP) have increased, as well as life expectancy at birth. In Chile there are more than 2 million 800 thousand EP, which corresponds to 1/6 of the Chilean population. The EP have a higher disease burden and mortality when facing surgery and in the postoperative period. Thus, this population frequently has longer hospital stays due to its degree of fragility, surgical complications or decompensation of its underlying pathologies, directly affecting health care systems. An inadequate preparation of the EP prior to surgery determined that the requirements of in-hospital as well as out-of-hospital care are extended, with the consequent which entails a higher cost in health. Current research underestimates the conditions of frailty and dependence in the EP. In addition, it is not routinely evaluated prior to surgery, as well as nutritional, metabolic, cognitive status and / or delirium screening is performed. There are accelerated recovery programs, which relate their interventions to specific pathologies; however, the age of the person is not taken into account. Surgical pre-habilitation interventions in the EP usually focus their efforts on physical and cardiovascular aspects, not including an integrative pre-surgical evaluation. Based on the foregoing, a prospective, interventional, longitudinal and randomized study has been proposed in a population of the EP who will undergo elective urology and coloproctology surgeries in two university hospitals (private and public). The objective of this study is to evaluate how the implementation of a timely pre-surgical conditioning (APO) protocol for frail elderly people reduces the days of hospital stay. The APO considers the most relevant aspects of physical and cardiovascular pre-habilitation, in addition to contemplating evaluations of frailty, dependence, cognitive status, screening for delirium, nutritional and metabolic.

NCT ID: NCT04769440 Completed - Anesthesia Clinical Trials

Effect of mgso4 on Oxygenation and Lung Mechanics in Morbidly Obese Patients During Bariatric Surgery

Start date: March 1, 2021
Phase: Phase 2
Study type: Interventional

The purpose of this trial is to study the effect of mgso4 infusion on oxygenation and lung mechanics in morbidly obese patients undergoing bariatric surgery

NCT ID: NCT04767867 Completed - Anesthesia Clinical Trials

Pre-oxygenation With Facemask Oxygen vs High-flow Nasal Oxygen vs High-flow Nasal Oxygen Plus Mouthpiece Oxygen

PREOX
Start date: August 1, 2020
Phase: N/A
Study type: Interventional

Pre-oxygenation increases oxygen reserves in the body to reduce the likelihood of oxygen desaturation on induction of general anaesthesia. Pre-oxygenation with facemask is the commonest method method of pre-oxygenation. High-flow nasal oxygen is a newer alternative. This study randomises participants to receive pre-oxygenation by one of three methods: facemask, high-flow nasal oxygen, high-flow nasal oxygen plus mouthpiece.

NCT ID: NCT04767685 Completed - Anesthesia Clinical Trials

The Bern Perioperative Biobank

BPBB
Start date: January 2011
Phase:
Study type: Observational

The goal of the research is to define clinically relevant molecular markers for increased risk of peri-/ postoperative organo-dysfunctions, inflammation, adverse events and disease progression. To better understand the perioperative impact the investigators aim to determine perioperative levels of molecular markers over time in the available samples and clinical data of the Bern perioperative Biobank (BPBB) cohort to finally increase quality of perioperative care of patients by permitting preventive measures to be taken early in patients at risk.

NCT ID: NCT04765046 Completed - Anesthesia Clinical Trials

The Influence of Age on EEG Signals and Consciousness During Anesthesia

TIARA
Start date: August 18, 2021
Phase: N/A
Study type: Interventional

This is a prospective, multi-center, non-invasive, interventional, data collection study to improve the current BIS algorithm in the elderly adult population.

NCT ID: NCT04762420 Completed - Anesthesia Clinical Trials

Sugammadex Dosing: Anaesthesiologist Clinical Perception Versus Quantitative Monitoring

Start date: February 1, 2019
Phase:
Study type: Observational

Many clinicians continue to rely on subjective evaluation in making decisions about the adequacy of neuromuscular function before tracheal extubation rather than using quantitative monitoring. The aim was to compare the sugammadex dose as suggested by senior anaesthesiologists (SSD) based on clinical experience versus the dose determined by quantitative monitoring (QSD) to determine if the subjective dose was appropriate.

NCT ID: NCT04757896 Completed - Anesthesia Clinical Trials

Costoclavicular Blockage for Upper Limb Surgery

Start date: December 25, 2020
Phase: N/A
Study type: Interventional

To evaluate the success of surgical anesthesia of lateral and medial approaches of the costoclavicular block in patients undergoing upper extremity surgery.

NCT ID: NCT04743193 Completed - Anesthesia Clinical Trials

Different Low-flow Sevoflurane Anesthesia Techniques

Start date: February 5, 2021
Phase:
Study type: Observational [Patient Registry]

After reaching 1 MAC level with 4 lt / min fresh gas flow and 2.5% sevoflurane concentration in the initial stage in 35 patients, anesthesia maintenance will be continued with 0.5 lt / min fresh gas flow and 2 -4% sevoflurane concentration with the target of 1 MAC. For 35 patients, after reaching 1 (MAC) level with 1 lt / min fresh gas flow and 8% sevoflurane concentration in the initial phase, maintenance of anesthesia will be continued with 0.5 lt / min fresh gas flow and 2 -4% sevoflurane concentration, targeting 1 MAC.

NCT ID: NCT04734119 Completed - Anesthesia Clinical Trials

Patient Satisfaction With Perioperative Anesthetic Care

Start date: December 1, 2018
Phase:
Study type: Observational

The doctor-patient relationship, medical competence and patient expectations influence patient satisfaction with anesthesia. Preoperatively all patients are routinely assessed by an anesthesiologist. However, in many centers, the anesthesiologist who performs the preoperative evaluation will not necessarily be the anesthesiologist who provides the intraoperative service. This study evaluated the effect of this practice on patient satisfaction, level of confidence and anxiety among adult patients undergoing elective surgery.