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Anesthesia clinical trials

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NCT ID: NCT05221190 Completed - Anesthesia Clinical Trials

Buccal Infiltration Anesthesia Versus Inferior Alveolar Nerve Block Anesthesia

Start date: September 1, 2021
Phase: N/A
Study type: Interventional

This study aims to evaluate the effectiveness of single buccal local infiltration when compared to buccal local infiltration with intrapapillary infiltration and inferior alveolar nerve block anesthesia in primary mandibular molar extractions.

NCT ID: NCT05214560 Completed - Anesthesia Clinical Trials

Prospective Clinical Evaluation of BD Spinal Needles

Start date: February 10, 2022
Phase:
Study type: Observational

Post-market, observational study to assess the real-world safety and efficacy of BD Spinal Needles used in an on-market fashion.

NCT ID: NCT05199883 Completed - Anesthesia Clinical Trials

The TI.VA Algorithm: A First-in-Humans Test.

TIVAly
Start date: December 1, 2020
Phase: N/A
Study type: Interventional

The TI.VA algorithm is a new method to titrate the anesthetic drug concentrations whenever the planned level of anesthesia results to be not appropriate to blunt the patient's reaction to surgical stimulation. TI.VA is a multiple inputs/multiple outputs algorithm. The control variables are the bispectral index (BIS) and the mean arterial pressure (MAP) combined in a decision-making matrix. The optimal range for the two control variables (BIS: 540-60 and MAP: 65-75 mmHg) identified the Optimal Anesthesia Zone (OAZ) at the center of the matrix. Any time one or both control variables escape from the PAZ, the algorithm proposes an intervention on the hypnotic and/or opioid levels (algorithm outputs). A First-in-Humans study was designed to capture preliminary data on the safety and performance of the TI.VA algorithm.

NCT ID: NCT05191966 Completed - Anesthesia Clinical Trials

Subcostal Approach to Anterior Quadratus Block Versus Thoracic Paravertebral Block for Laparoscopic Nephrectomy

Start date: September 1, 2022
Phase: N/A
Study type: Interventional

In this study, it was aimed to evaluate the effects of subcostal anterior quadratus lumborum block (S-QLB3) and thoracic paravertebral block (TPVB) on postoperative acute pain scores and opioid consumption in the first 24 hours after laparoscopic nephrectomy surgery.

NCT ID: NCT05191953 Completed - Anesthesia Clinical Trials

ESPB vs.Combination of ESPB and Superficial PIPB in Cardiac Surgery

Start date: January 26, 2022
Phase: N/A
Study type: Interventional

Cardiac surgery is associated with significant postoperative pain. Pain control is an essential part of enhanced recovery protocols. The aim of this study is to evaluate and compare the analgesic efficacies of erector spinae plane block (ESPB) and the combination of ESPB and superficial parasternal intercostal plane block (PIPB) in patients undergoing elective cardiac surgery.

NCT ID: NCT05189431 Completed - Anesthesia Clinical Trials

Peripheral Perfusion Index During Induction of Anaesthesia

Start date: July 1, 2018
Phase:
Study type: Observational [Patient Registry]

We wish to study the feasibilty of using the peripheral perfusion index as a supplementary monitor during induction of general anesthesia

NCT ID: NCT05188547 Completed - Anxiety Clinical Trials

Information Retention After Video (Augmented) Preoperative Anesthesiological Education

Start date: February 1, 2022
Phase: N/A
Study type: Interventional

Patient education is continuously becoming more important to enable patients to participate in making decisions regarding their medical treatment. Specifically, this is also the case for preoperative education on anesthesia. Worldwide, there are many initiatives to improve preoperative patient education and subsequent level of knowledge of anesthesia, for example by using digital aids. The demand for such aids has increased significantly since the start of the Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2) pandemic to facilitate remote preoperative anesthesiological screening. Although many videos to educate patients on anesthesia have been developed and circulate on the internet, there has been little effort to compare this method of educating patients with the traditional one-on-one conversation between the anesthesiologist and the patient. Objective: To compare short, mid-and long term retention of knowledge after education on anesthesia by watching a video to the traditional one-on-one explanation by the anaesthesiologist.

NCT ID: NCT05187039 Completed - Anesthesia Clinical Trials

Bariatric Electrical Impedance Tomography

Start date: October 19, 2021
Phase:
Study type: Observational

This study investigates under controlled conditions the variation of poorly ventilated lung units (silent spaces) in obese patients scheduled for laparoscopic bariatric surgery in the perioperative phase.

NCT ID: NCT05185167 Completed - Anesthesia Clinical Trials

Comparison of the Genotoxicity of Desflurane and Propofol

Start date: January 17, 2022
Phase: N/A
Study type: Interventional

The purpose of this study is to evaluate if the anesthetics propofol and desflurane can damage DNA according to comet essay in patients submitted to lumbar disc surgery.

NCT ID: NCT05171608 Completed - Anesthesia Clinical Trials

Preoperative Ultrasound-based Protocol for Optimization of Fluid Therapy to Prevent Early Intraoperative Hypotension

Start date: December 15, 2021
Phase: N/A
Study type: Interventional

Background: Intraoperative hypotension increases 30-day mortality and the risks of myocardial injury and acute renal failure. Patients with inadequate volume reserve before the induction of anesthesia are highly exposed. The identification of latent hypovolemia is therefore crucial. Ultrasonographic measurement of the inferior vena cava collapsibility index (IVCCI) is able to detect volume responsiveness in circulatory shock and growing evidence support the theory that higher IVCCI can predict intraoperative hypotension. The aim of the present study is to evaluate the potential benefit of an ultrasound-based protocol for preoperative fluid optimization. The investigators will perform a randomized-controlled study involving elective surgical patients. An ultrasound-based protocol (USP) arm and a conventional fluid therapy group (CFT) are to be formed. Ultrasound examinations will be performed twice in both groups: 2 hours and 30 minutes preoperatively. The inferior vena cava and the anterior lung fields will be scanned. In the USP group the participants will receive fluid therapy according to the ultrasonographic findings: high level of IVCCI and absence of signs of pulmonary edema will indicate fluid therapy. In the CFT group the attending anesthesiologist (blinded to the results of ultrasonography) will order fluid therapy on the basis of daily routine and clinical judgement. The investigators will evaluate the incidence of intraoperative hypotension (primary outcome), postoperative metabolic status and organ functions and the amount of the administered intravenous fluids in both groups.