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Anesthesia clinical trials

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NCT ID: NCT06092671 Not yet recruiting - Anesthesia Clinical Trials

Effect of Family-centered Perioperative Care for Anesthesia (FPCA) on Incidence of Emergency Delirium and Postoperative Maladaptive Behaviors in Children After Surgery

Start date: October 2023
Phase: N/A
Study type: Interventional

Emergency delirium (ED) is one of the most common postoperative complications in pediatric patients and is associated with an increase of hospitalization time, healthcare costs, and increased incidence of postoperative maladaptive behaviors (POMBs). There is no clear pharmacological or non-pharmacological interventions that are effective in reducing the incidence of ED or POMBs. Therefore, the investigators aimed to assess whether family-centered perioperative care for anesthesia (FPCA) reduce the incidence of ED or POMBs in children compared with conventional preoperative pharmacological interventions.

NCT ID: NCT06090396 Recruiting - Anesthesia Clinical Trials

Non-invasive Cardiac Index in Children

NICIM
Start date: October 15, 2023
Phase:
Study type: Observational

This study investigates the level of agreement of two non-invasive cardiac output monitors (transthoracic echocardiography and electrical cardiometry) in young children under anesthesia.

NCT ID: NCT06084039 Completed - Anesthesia Clinical Trials

Reducing the Carbon Footprint Through Education on the Effects of Inhalation Anesthetics on Global Warming

Start date: August 1, 2022
Phase:
Study type: Observational

Inhalation anesthetics, such as desflurane, are identified as contributors to global warming, with the European Union planning to ban desflurane in 2026 due to its impact. The World Federation of Societies of Anesthesiologists (WFSA) has published guidelines to reduce air pollution related to inhalation anesthetics. Inhalation anesthetics account for a significant portion of carbon dioxide equivalent (CO2e) emissions in hospitals and surgery. Various anesthetics have different global warming potentials (GWP100), with desflurane having the highest GWP100. Nitrous oxide and isoflurane, although having lower GWP100, can also impact the environment negatively. Studies have shown that educating anesthesia staff about the environmental impact of desflurane and nitrous oxide can lead to significant reductions in their usage, resulting in lower CO2e emissions and cost savings. However, in some regions like Korea, awareness of the environmental impact of inhalation anesthetics is limited. The authors plan to analyze the impact of education on anesthesiologists regarding inhalation anesthetics and assess changes in their usage and CO2e emissions in clinical settings. The goal is to demonstrate that education can positively influence environmental outcomes and reduce economic losses.

NCT ID: NCT06082856 Recruiting - Anesthesia Clinical Trials

Evaluation of the Hemodynamic Effect of Dexmedetomidine in Scheduled Outpatient Surgery

DEXCOEUR
Start date: October 19, 2023
Phase: N/A
Study type: Interventional

Ambulatory surgery is increasingly used in anesthesia. In case of general anesthesia, it is recommended to use anesthesia molecules with a short half-life and low doses of opiates to ensure a rapid awakening and to prevent nausea and vomiting by systematic administration of anti-emetics during the operation. Opiates (including sufentanil) have recently been called into question because of the nausea and vomiting and the delay in waking up induced by these molecules. To combat these side effects, the authors have proposed either to reduce the doses or to substitute them with dexmedetomidine, a sedative antihypertensive drug. Recent studies have demonstrated that opiates used in general anesthesia can be replaced by dexmedetomidine. However, literature data are controversial concerning the hemodynamic impact. No study has compared the hemodynamic profile of opioid-free anesthesia with dexmedetomidine versus conventional anesthesia with opioids. The ambulatory context lends itself to the use of dexmedetomidine because it is aimed at a population without strong cardiac pathology, concerns non-major interventions, with the need to optimize pain and side effects. The study authors therefore wish to compare the effects of induction of general anesthesia with low-dose Dexmedetomidine versus sufentanil, on post-induction hemodynamic stability in scheduled outpatient surgeries. The investigators hypothesize that hemodynamic stability at induction of general anesthesia with low-dose dexmedetomidine is not inferior to that obtained with sufentanil in scheduled ambulatory surgeries.

NCT ID: NCT06080100 Recruiting - Anxiety Clinical Trials

RELIEF OF PSYCHOEMOTIONAL STRESS USING XENON SEDATION

Start date: November 1, 2023
Phase: Early Phase 1
Study type: Interventional

The goal of this clinical trial is to propose for implementation and evaluate the effectiveness of xenon sedation for the relief of psychoemotional stress disorder before the operation of refractive laser vision correction patients with high anxiety and stress instability who underwent xenon analgosedation before refractive laser vision correction. The main question[s] it aims to answer are: 1. To develop a method of xenon sedation in patients with a high level of psychoemotional stress before surgery - refractive laser vision correction. 2. To evaluate the effect of inhaled xenon anesthesia in a sub-narcotic dose on the duration of surgery, satisfaction of surgeons and patients with anesthesia, the level of postoperative pain in patients in comparison with anxiolytics. The following will be studied: the level of preoperative anxiety, the dynamics of glycemia and blood cortisol levels, heart rate variability, electrical microamplitudes of the ECG signal, the anti-stress and analgesic effect of xenon. If there is a comparison group: the researchers will compare [the group with xenon sedation and the control group] to see if there is [an anti-stress effect of xenon in patients before laser vision correction].

NCT ID: NCT06079710 Not yet recruiting - Anesthesia Clinical Trials

Effect of Intraoperative and Awakening Electroencephalogram on Awakening Agitation After General Anesthesia in Children

Start date: November 1, 2023
Phase:
Study type: Observational

The purpose of this study was to analyze the relationship between intraoperative and awakening electroencephalogram waveforms and awakening agitation after general anesthesia in children

NCT ID: NCT06078228 Enrolling by invitation - Anesthesia Clinical Trials

Prediction of Hypotension During Induction of General Anesthesia

Start date: September 24, 2023
Phase:
Study type: Observational [Patient Registry]

Post induction hypotension is closely related to postoperative complications. Patients are at high risk of hypotension due to preexisting hypovolemia and the vasodilatory effects of induction agents. Ultrasonographic measurement of the Carotid artery corrected flow time and internal jugular vein collapsibility index may predict post induction hypotension.

NCT ID: NCT06076096 Completed - Anesthesia Clinical Trials

SIFIB As an Anesthesia Method for Lower Extremity Surgeries

Start date: March 1, 2022
Phase:
Study type: Observational

The Ultrasound-guided Supra-inguinal Fascia Iliaca Block (SIFIB) is an advanced regional anesthesia technique strategically directed at the three primary nerves of the lumbar plexus. As the scope of regional anesthesia methods continues to grow in clinical application, this approach emerges as a versatile method. It can be used independently for pain management or as the primary anesthetic method, particularly in well-selected patients undergoing isolated limb surgeries or in combination with other regional anesthesia approaches.

NCT ID: NCT06074471 Recruiting - Anesthesia Clinical Trials

Motor Sparing Supraclavicular Block

Start date: September 25, 2023
Phase: N/A
Study type: Interventional

This study aims to compare MS-SCBPB and SCBPB in the duration of postoperative analgesia, time to first analgesic request (VAS ≥40 mm), pain scores, motor power, and side effects.

NCT ID: NCT06073197 Completed - Anesthesia Clinical Trials

Comparison of Erector Spinae Block and Combined Deep and Superficial Serratus Anterior Plane Block

Start date: July 2, 2020
Phase: N/A
Study type: Interventional

Objective: The authors hypothesized that combined deep and superficial serratus anterior plane block (SAPB) is as effective as erector spinae plane block (ESPB) for intraoperative and postoperative analgesia for video-assisted thoracoscopic surgery. Design: A prospective randomized controlled study. Participants: Adult patients undergoing elective video-assisted thoracoscopic surgery. Interventions: Preoperative SAPB or ESPB implementation.