Anesthesia; Reaction Clinical Trial
Official title:
Target-controlled Propofol Infusion as a Technique of Anesthesia for Surgery of Hip Fracture Under Ultrasound Guidance Lumbar and Sacral Plexus Block or Lumbar, Sacral and Paravertebral Nerve Block in the Elderly
The investigators aim to examine target-controlled propofol infusion as a technique of anesthesia for surgery of hip fracture under ultrasound guidance lumbar and sacral plexus block or lumbar, sacral and paravertebral nerve block in the elderly; and to evaluate which regional anesthesia was more sufficient for the old.
Eighty patients with American Society of Anesthesiologists(ASA) Ⅰ-Ⅲ older than 80 years are randomly assigned to 2 groups: a lumbar and sacral plexus block(LS) group with 20ml 0.5% ropivacaine at lumbar plexus(level L3-4) and 10ml 0.5%ropivacaine at sacral plexus; a lumbar, sacral plexus and paravertebral nerve block(LSP) group with 20ml 0.5% ropivacaine at lumbar plexus(level L3-4) , 10ml 0.5%ropivacaine at sacral plexus and 10ml 0.5%ropivacaine at paravertebral nerve(level L1). The target-controlled propofol infusion is started immediately after positioning the patient on the operating table. The initial target concentration was 0.5μg/mL. The infusion rate is adjusted every 5min by increasing or decreasing the target concentration by 0.2μg/mL steps based on the patients' respiratory rate(RR), blood pressure(BP), heart rate(HR), and level of sedation(score of 5 on Ramsay Sedation Scale ). The minimal, maximal, optimal target concentration, cumulative propofol dose, frequency of spontaneous movement and incidences of associated complications are recorded. Patients were phoned for followup and questioned for activity status in one year. If the patients were dead, date of death; if they survived, daily living activity questioned. ;
Allocation: Randomized, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Parallel Assignment, Masking: Single Blind (Subject), Primary Purpose: Treatment
Status | Clinical Trial | Phase | |
---|---|---|---|
Recruiting |
NCT05358535 -
Propofol and Etomidate Admixtures Comparisons Trial (PEAC Trial)
|
Phase 3 | |
Recruiting |
NCT03839784 -
Building a Platform for Precision Anesthesia in the Geriatric Surgical Patient
|
||
Completed |
NCT04399226 -
Dexmedetomidine-Propofol and Ketamine-Propofol During Upper Gastrointestinal System Sedation
|
||
Recruiting |
NCT05024838 -
Prediction of Block Height of Spinal Anesthesia
|
||
Completed |
NCT05383417 -
No Post Intubation Laryngeal Symptoms
|
N/A | |
Completed |
NCT03276533 -
Dexmedetomidine Combined With Lidocaine Infusion Affect Inflammation Cytokines
|
N/A | |
Recruiting |
NCT01329874 -
Anesthetic Efficacy of Gow-Gates Versus Conventional Inferior Alveolar Nerve Block Techniques
|
N/A | |
Completed |
NCT01651988 -
Efficacy of Ketamine-Propofol for Short Surgical Procedures
|
Phase 4 | |
Recruiting |
NCT01898897 -
Influence of Anesthesia Technique on Postoperative Evolution After Urogenital Surgical Interventions
|
N/A | |
Recruiting |
NCT04435834 -
Individual Cerebral Hemodynamic Oxygenation Relationships
|
Phase 4 | |
Not yet recruiting |
NCT02143362 -
Dexmedetomidine Combined With the Closed Loop of Target Controlled Infusion of Propofol for Anesthesia With Intraoperative Wake up
|
Phase 4 | |
Completed |
NCT02429323 -
Endotracheal Intubation With Sevoflurane in Surgical Pediatric Patients
|
N/A | |
Completed |
NCT02136641 -
Study of Comparison of the Effectiveness of Three Diagrams for Sedation in Spinal Anesthesia
|
Phase 4 | |
Not yet recruiting |
NCT05869578 -
Registry of Anesthesia and Perioperative Medicine
|
||
Completed |
NCT03134677 -
The Effects of Different Anesthetic Techniques on QT, Corrected QT (QTc), and P Wave Dispersions in Cesarean Section
|
Phase 4 | |
Enrolling by invitation |
NCT02355093 -
Adductor Canal Block Versus Femoral Nerve Block for Analgesia After Anterior Cruciate Ligament Reconstruction Arthroscopically
|
Phase 4 | |
Completed |
NCT03161275 -
Measurement of the Cerebral Saturation for Assessment of Safety of Epidural Anaesthesia During Abdominal Surgery
|
N/A | |
Recruiting |
NCT03237429 -
The Relationship Between BCM, Arterial Stiffness and Hemodynamic Instability During Induction of General Anesthesia
|
||
Active, not recruiting |
NCT05610007 -
Comparison of Hyperbaric Prilocaine 2% 50 Mg and Hyperbaric Bupivacaine 0.5% 12.5 Mg Against Spinal Anesthesia Recovery Time in Cystoscopy Procedure
|
Phase 4 | |
Completed |
NCT04906772 -
Dexmedetomidine-ketamine Versus Propofol-ketamine for Sedation During Endoscopy in Hepatic Patients
|
Phase 4 |