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Anesthesia, Obstetrical clinical trials

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NCT ID: NCT05099055 Completed - Analgesia Clinical Trials

Dexmedetomine as Adjuvant for Spinal Anesthesia in Elective Cesarian Sections : a Pilot Study

Start date: March 15, 2022
Phase: Phase 3
Study type: Interventional

The proposed pilot study is a prospective, randomized, controlled, double-blind, single-center pilot study.The aim of this pilot project is to evaluate the feasibility of a phase III study on the use of dexmedetomidine in intrathecal in the context of elective cesarean section. The target population for the study will be adult pregnant women undergoing elective cesarean section under spinal anesthesia. This study will be carried out at a single site, the CHU Sainte-Justine as part of a research internship as part of the anesthesiology residency program at the University of Montreal.

NCT ID: NCT05091294 Completed - Anesthesia, Spinal Clinical Trials

The Effect of Injection Rate of Local Anesthetic in Caesarean Section

Start date: February 11, 2020
Phase: N/A
Study type: Interventional

This randomized double-blind study aimed to compare the effects of two different subaracnoid lokal anesthetic injection rate in cesarean section. Totally 67 patients were included. The groups were compared in terms of maximum sensory and motor block level, time to reach T6 level, hemodynamic changes and nausea- vomiting saved.

NCT ID: NCT04205344 Completed - Clinical trials for Anesthesia, Obstetrical

Subarachnoid Bupivacaine in Obese Patients Undergoing Cesarean Delivery

Start date: February 1, 2017
Phase: Phase 4
Study type: Interventional

This study evaluates the effect of subarachnoid hyperbaric bupivacaine on mean arterial blood pressure (MAP) of pregnant patients with obesity undergoing cesarean section half of the patients will receive subarachnoid hyperbaric bupivacaine at a dose of 5 mg while the other half will receive a dose of 10 mg

NCT ID: NCT03333902 Completed - Clinical trials for Anesthesia, Obstetrical

The Comparison Of Nerve Blocks In Cesarean Delivery

Start date: December 1, 2017
Phase: N/A
Study type: Interventional

The purpose of this study is to investigate the effect of different kinds of popular peripheral nerve blocks for postoperative analgesia after cesarean delivery is completed, compared with traditional epidual analgesia.

NCT ID: NCT03167905 Active, not recruiting - Clinical trials for Depression, Postpartum

CODEPAD (Collaborative Outcomes of DEpression and Pain Associated With Delivery)

CODEPAD
Start date: June 15, 2017
Phase: Phase 2/Phase 3
Study type: Interventional

Postnatal depression affects about 10-15% of women after childbirth. Approximately 3-5% of women experience a moderate-to-severe depression that requires medical attention. This study aims to investigate the implication of pain relief choice in reducing the postnatal depression of women who deliver their babies.

NCT ID: NCT03164096 Recruiting - Clinical trials for Anesthesia, Obstetrical

The Effect of Some Parturients' Characteristics on Sensory Block Level After Spinal Anesthesia

Start date: June 1, 2017
Phase: Phase 4
Study type: Interventional

Although the exact mechanism remains unknown, the association of pregnancy and decreased local anesthetic requirement is clear. demonstrated that more local anesthetic is required for cesarean section under combined spinal-epidural anesthesia in preterm compared with term patients.

NCT ID: NCT03133091 Completed - Analgesia, Epidural Clinical Trials

Epidural Analgesia During Labour

PIEBvsPCEA
Start date: September 2015
Phase: Phase 3
Study type: Interventional

Randomized single blind trial based on comparing the way the local anesthetic is dosificated during labour. The pain control is evaluated and compared with both dosage techniques (PCEA vs PIEB)using levobupivacaine and fentanyl. The primary objective is to see no differences in pain control(VAS, Visual Analog Scale). The secondary goals are the differences in motor block(Bromage Scale), satisfaction (Likert Scale), the outcome (eutocic, instrumental o cesarean section), second stage of labour time, newborn´s Apgar and pH and total dosis and secondary effects of local anesthetic.

NCT ID: NCT03090295 Completed - Clinical trials for Anesthesia,Obstetrical

Palpation and ACCURO for Placing Spinal in C-section

Start date: March 13, 2017
Phase: N/A
Study type: Interventional

The Accuro is a three dimensional handheld ultrasound device. This device uses sound waves to create pictures of the spine in three dimensions. This may allow the physician to view the spine in more detail for procedures such as spinal anesthesia and other diagnostic procedures. We aim to assess the benefit of using both the Accuro and traditional landmark palpation technique to determine accurate spinal level in women who undergo cesarean section. This study will also assess provider preference for use of both Accuro and palpation compared with palpation alone or use of Accuro alone. Anesthesia Providers will first identify the L4/L5 space using the traditional technique of palpating the iliac crests to estimate spinal level, which will be marked with a single dot from a marking pen. The provider will then use the Accuro 3000 to identify the L4/L5 interspace. Results will be compared to results obtained in IRB 18070 "Handheld 3D lumbar spine navigation: A clinical validation study RM002" where subjects who were undergoing a C-section were randomized to either palpation or Accuro alone.

NCT ID: NCT02958215 Completed - Anesthesia, Spinal Clinical Trials

Phenylephrine and Hypotension During Spinal Anesthesia for Cesarean Section

Start date: June 2016
Phase: Phase 2
Study type: Interventional

Pregnant women with a positive preoperative Supine stress test were found to be a subgroup at increased risk of symptomatic hypotension after spinal anesthesia