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Anesthesia, Conduction clinical trials

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NCT ID: NCT05313269 Completed - Clinical trials for Arthroplasty, Replacement, Knee

Inter-fascial Plane Between the SArtorius Muscle and FEmoral Artery (ISAFE)

ISAFE
Start date: April 28, 2022
Phase: N/A
Study type: Interventional

Total knee arthroplasty (TKA) is a frequent performed surgery. Adequate pain management is an important feature. Analgesic duration of single shot nerve blocks is limited to no more than 24h. Conversely, the use of continuous nerve block (CNB) through a perineural catheter and infusion of local anesthetic may increase duration of analgesia and provide better outcomes. Continuous adductor canal block (CACB) has been proven superior when compared to single-injection adductor canal block (SACB) for TKA analgesia. However, safety concerns such as intravenous insertion, nerve injury, or catheter displacement must always be considered. The purpose of this study is to evaluate the Inter-fascial Plane between SArtorius Muscle and FEmoral Artery (ISAFE) approach for adductor canal catheter placement, in terms of catheter dislodgment, clinical effectiveness and complications, in comparison with the classical approach, as TKA postoperative analgesia modality. We hypothesize that ISAFE approach can result in a smaller rate of dislodgments in the way that it increases the clinical benefit of CACB.

NCT ID: NCT04996290 Completed - Pain, Postoperative Clinical Trials

Combined PENG and LFCN Block for Total Hip Arthroplasty

Start date: June 1, 2020
Phase: N/A
Study type: Interventional

A clinical trial investigating the effect of a combined locoregional anesthesia technique on the postoperative analgesia outcomes after a total hip arthroplasty. A PENG block will be used in combination with a LFCN block. The results will be compared to a control group that is solely treated with intravenous analgesia. This technique aims to provide improved pain scores after surgery without interference of revalidation.

NCT ID: NCT04928794 Completed - Clinical trials for Anesthesia, Conduction

Thermal-Imaging Comparison of Nerve Blocks for Bilateral Mastectomy

Start date: May 19, 2021
Phase: N/A
Study type: Interventional

This is a one-armed trial of two regional anesthesia (peripheral nerve block) techniques to provide postoperative analgesia after bilateral mastectomy. The two techniques are paravertebral block and erector spinae plane (ESP) block. Patients will serve as their own controls, with one block technique applied on one side of the body and the other technique contralaterally. Anatomical distribution of block effectiveness will be assessed with thermal imaging, and this distribution will be visually compared between the two techniques.

NCT ID: NCT04414488 Completed - Clinical trials for Anesthesia, Conduction

The Impact of Regional Anaesthesia on Hormone Levels in Thoracic Surgery.

Start date: May 1, 2018
Phase:
Study type: Observational

Basic aspects of thoracic anaesthesia are general anesthesia often combined with regional anesthesia, intubation with double lumen tube and separation of lung ventilation. Proper assessment of pain and adequate analgesia in intraoperative and postoperative period is a challenging issue for medical practitioners. Intraoperative trauma may lead to many metabolic implications and disturbance of haemostasis, what can be reflected in change of blood and saliva hormone and other substance levels. The aim of this study is to assess the impact of regional anesthesia on hormone levels in patients requiring videothoracoscopic procedures.

NCT ID: NCT04355468 Completed - Thoracic Surgery Clinical Trials

Opioid Free Anesthesia in Thoracic Surgery

Start date: December 2015
Phase: N/A
Study type: Interventional

Proper assessment of pain and adequate analgesia in thoracic surgery is a challenging issue for medical practitioners. Basic aspects of thoracic anaesthesia are general anesthesia, intubation with double lumen tube and separation of lung ventilation, however proper analgesia needs to be standardized. Role of opioids in this clinical setting is reduced due to high risk of respiratory system complications. Instead, use of opioid free anaesthesia and regional anaesthesia is proposed. The aim of this study is to compare the use of opioid anaesthesia with opioid free anaesthesia and paravertebral block.

NCT ID: NCT03889223 Completed - Clinical trials for Anesthesia, Conduction

Ultrasonographic and Comfort Comparison of Sitting Fetal Cross-legged Position With Lateral Decubitus Fetal Position

Start date: March 20, 2019
Phase: N/A
Study type: Interventional

A prosperous neuraxial anesthesia positioning ensures a raised chance of successful needle placement. The primary aim is to compare "Sitting Cross-legged Fetal Position -SCF" with "Lateral Decubitus Fetal Position-LDF" anatomically via sonography. Secondary aim is to compare their comfort.

NCT ID: NCT03741465 Completed - Clinical trials for Anesthesia, Conduction

A New Neuraxial Position Technique " The Anatolian Sitting Position- Sitting Fetal Cross-legged"

Start date: June 1, 2018
Phase: N/A
Study type: Interventional

A prosperous neuraxial anesthesia positioning ensures a raised chance of successful needle placement. The primary aim is to compare "The Anatolian sitting position-ASP" with "The Sitting Fetal Position-SFP" sonographically. Secondary aim is to compare their comfort.

NCT ID: NCT03688269 Completed - Dexamethasone Clinical Trials

Minimal Effective Concentration (EC90) of Ropivacaine

AxiRopiDexa
Start date: October 5, 2018
Phase: Phase 3
Study type: Interventional

Prospective up and down sequential evaluation of the minimal effective concentration of perineural ropivacaine for 90% success in axillary brachial plexus block with the injection of intravenous dexamethasone or saline placebo during regional anesthesia performance

NCT ID: NCT03623230 Completed - Pain, Postoperative Clinical Trials

Concentration Effect of Local Anesthetics on Femoral Nerve Block Efficiency

Start date: August 10, 2018
Phase: Phase 4
Study type: Interventional

US-guided femoral nerve block is used effectively in post-operative pain management in the surgical treatment of the lower extremity. However, the volume and concentration of the local anesthetic drug to be administered remains controversial. In this prospective, randomized, double-blinded study, patients who underwent unilateral primary total knee arthroplasty and successfully performed spinal anesthesia with standard method and dosage, will be selected for US-guided femoral nerve block after the operation. Patients will be divided into three groups with simple randomization. The First group will be determined as the control group (GCont) and only dressing will be applied to the patients. For second group(G125), 0,125% 20 ml local anesthetic and for the third group (G25), 0,25% 10 ml local anesthetic will be administered to the femoral nerve without changing the drug dose (25 mg bupivacaine). Whether there is a difference between post-op analgesia durations, motor block formation, mobilization time and 90° flexion time between the groups will be investigated.

NCT ID: NCT03623035 Completed - Osteoarthritis, Hip Clinical Trials

Pain and Sensation After Regional Anesthesia - Pilot Study

Start date: August 16, 2018
Phase:
Study type: Observational

This study aims to determine spinal resolution and pain levels after the placement of a lumbar plexus block (LPB) and spinal for total hip replacement procedure. This is a pilot study that looks to collect information in order to design a larger, more significant study comparing Quadratus Lumborum blocks (QLB) and Lumbar Plexus blocks.