Erythropoietin + Iron Therapy for Anemic Patients Undergoing Aortic Valve Replacement — EPICURE  

Anemia Clinical Trial

Official title: Combined ErythroPoietin and Iron Therapy for AnemiC Patients With Severe Symptomatic Aortic Stenosis Undergoing Transcatheter Aortic Valve REplacement- The EPICURE Trial A Prospective Double Blind Randomized Trial

Status Completed

Clinical Trial Summary

The objective of the study is to evaluate the efficacy of Erythropoietin (EPO) (+ iron) in reducing the rate of red blood cell transfusion requirements in patients with aortic stenosis undergoing transcatheter aortic valve replacement.

Clinical Trial Description

STUDY DESIGN

Prospective randomized double blind study including patients diagnosed with severe symptomatic aortic stenosis and anemia undergoing aortic valve replacement. The patients will be identified in the cardiac surgery / aortic stenosis outpatient clinic or in the hospitalization department of the Institut Universitaire de Cardiologie et de Pneumologie de Quebec.

SAMPLE SIZE

100 patients (50 patients per group). ;

Related Conditions & MeSH terms

• Anemia
• Aortic Stenosis
• Aortic Valve Stenosis
• Constriction, Pathologic

• NCT number: NCT02390102
• Study type: Interventional
• Source: Centre de Recherche de l'Institut Universitaire de Cardiologie et de Pneumologie de Quebec
• Status: Completed
• Phase: Phase 3
• Start date: June 2012
• Completion date: June 2016