Anemia Clinical Trial
Official title:
Assessment of Efficacy & Safety of Recombinant Human Erythropoietin -Alpha, (rHu-EPO-Alpha) in Patients With Anemia of Chronic Renal Failure.
To establish the efficacy and Safety of rHu-EPO-alpha in patients with anemia of Chronic Renal Failure.
Despite impressive advances in the safety of the blood supply, the search for therapeutic
alternatives to blood continues. Recombinant Human Erythropoietin (rHu-EPO), along with
iron, vitamin B12, and folic acid, has been recommended as a specific medication that should
be used instead of blood transfusion if the clinical condition of the patient permits
sufficient time for these agents to promote erythropoiesis.
In normal physiological conditions Erythropoietin is produced in the kidney and stimulates
the division and differentiation of committed erythroid progenitors in the bone marrow.
rHu-EPO is a glycoprotein which stimulates red blood cell production. Epoetin alfa, a 165
amino acid glycoprotein manufactured by recombinant DNA technology, has the same biological
effects as endogenous rHu-EPO.
;
Allocation: Non-Randomized, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Single Group Assignment, Masking: Open Label, Primary Purpose: Treatment
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