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Comparison Study of Two Iron Compounds for Treatment of Anemia in Hemodialysis Patients — COPEFER  

Anemia of Chronic Kidney Disease Clinical Trial

Official title:
Continuous Versus Periodic Intravenous Iron Supplementation in Maintenance Hemodialysis Patients

Clinical Trial Summary

Patients with end-stage kidney disease on maintenance hemodialysis frequently require iron supplementation to compensate for ongoing iron losses, and to maintain hemoglobin levels with or without additional use of erythropoiesis-stimulating agents (ESA).

The investigators aim to compare two different intravenous iron preparations, ferric carboxymaltose and iron sucrose in 140 hemodialysis patients. The investigators primary objective is to assess whether both agents are equally effective to maintain a target haemoglobin within 10-12 mg/dl. The investigators will also measure ferritin, transferrin, transferrin saturation, and how much ESA therapy is administered.

Patients will be randomly assigned to either treatment group and followed in parallel over an active study period of 40 weeks.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT02198495
Study type Interventional
Source Medical University of Vienna
Contact
Status Completed
Phase Phase 4
Start date September 2014
Completion date May 2019
View Details
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