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Anemia, Iron Deficiency clinical trials

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NCT ID: NCT02962648 Completed - Clinical trials for Iron Deficiency Anemia

An Extension Trial to Assess the Safety of Re-dosing of Iron Isomaltoside/Ferric Derisomaltose (Monofer®/Monoferric®)

FERWON-EXT
Start date: January 9, 2017
Phase: Phase 3
Study type: Interventional

Evaluate safety and efficacy of intravenous (IV) iron isomaltoside/ferric derisomaltose re-dosing, in subjects who were previously treated with iron isomaltoside/ferric derisomaltose.

NCT ID: NCT02949947 Terminated - Clinical trials for Malignant Neoplasms of Mesothelial and Soft Tissue

Efficacy of Ferric Carboxymaltose in Gastrointestinal Stromal Tumor (GIST) Patients With Iron Deficiency Anemia (IDA) Receiving Systemic Therapy

Start date: December 18, 2017
Phase: Phase 2
Study type: Interventional

The goal of this clinical research study is to compare Injectafer® (ferric carboxymaltose) with an iron supplement to learn which may be more effective in improving red blood cell counts in patients who have iron-deficiency anemia (a low red blood cell count) because of a gastrointestinal stromal tumor (GIST) and/or systemic therapy. The safety of ferric carboxymaltose will also be studied. This is an investigational study. Ferric carboxymaltose is FDA approved and commercially available to treat iron deficiency anemia; however, it is considered investigational to use in patients who have cancer-related or systemic therapy-related anemia. Up to 50 participants will take part in this study. All will be enrolled at MD Anderson.

NCT ID: NCT02949765 Recruiting - Celiac Disease Clinical Trials

Effects of a Dietary Approach to Iron Deficiency in Premenopausal Women Affected by Celiac Disease

Start date: December 2015
Phase: N/A
Study type: Interventional

Anemia and sideropenia are a common effect of untreated celiac disease. In a portion of patients a certain degree of hypoferritinemia persist after the diagnosis, despite a good compliance and clinical response to gluten-free diet. These patients are usually premenopausal women in whom the cyclic menstrual bleeding and the oral iron intake are not balanced. The aim of the study is to compare the efficacy of a pharmacological therapy, frequently not tolerated, and a dietary approach through a iron-rich diet in this subset of patients.

NCT ID: NCT02941081 Completed - Clinical trials for Iron Deficiency, Anaemia in Children

A Novel Nano-iron Supplement to Safely Combat Iron Deficiency and Anaemia in Young Children: a Doubleblind Randomised Controlled Trial

IHAT-Gut
Start date: January 8, 2018
Phase: Phase 2
Study type: Interventional

This study aims to determine whether IHAT is non-inferior to ferrous sulphate at correcting iron deficiency and anaemia, and if IHAT does not increase diarrhoea risk in young children living in rural and resource-poor areas of the Gambia. The study hypothesis is that IHAT will eliminate iron deficiency and improve haemoglobin levels in young children without increasing infectious diarrhoea or promoting inflammation in the gut.

NCT ID: NCT02940886 Completed - Clinical trials for Iron Deficiency Anemia

Iron Isomaltoside/Ferric Derisomaltose vs Iron Sucrose for the Treatment of Iron Deficiency Anemia (IDA)

Start date: November 8, 2016
Phase: Phase 3
Study type: Interventional

Evaluate safety and efficacy of iron isomaltoside/ferric derisomaltose (Monofer®/Monoferric®) compared with iron sucrose (Venofer®), in subjects diagnosed with IDA.

NCT ID: NCT02940860 Completed - Clinical trials for Chronic Kidney Disease

Iron Isomaltoside/Ferric Derisomaltose vs Iron Sucrose for Treatment of Iron Deficiency Anemia in Non-Dialysis-Dependent Chronic Kidney Disease

Start date: November 29, 2016
Phase: Phase 3
Study type: Interventional

Evaluation of safety and efficacy of iron isomaltoside/ferric derisomaltose compared with iron sucrose, in subjects with both non-dialysis-dependent chronic kidney disease (NDD-CKD) and iron deficiency anaemia (IDA).

NCT ID: NCT02937454 Completed - Heart Failure Clinical Trials

Study to Compare Ferric Carboxymaltose With Placebo in Patients With Acute Heart Failure and Iron Deficiency

Affirm-AHF
Start date: April 3, 2017
Phase: Phase 4
Study type: Interventional

Study to Compare Ferric Carboxymaltose With Placebo in Patients With Acute Heart Failure and Iron Deficiency (Affirm-AHF)

NCT ID: NCT02916654 Recruiting - Celiac Disease Clinical Trials

Sucrosomial Iron in Patients With Celiac Disease and IDA

Start date: April 2015
Phase: N/A
Study type: Interventional

Sucrosomial iron (Sideral® Forte) is a preparation of ferric pyrophosphate conveyed within a phospholipid membrane associated with ascorbic acid, is a new-generation oral iron which shows a high gastrointestinal absorption and high bioavailability with a low incidence of side effects due to lack of any direct contact with intestinal mucosa. In comparison with the other standard oral iron preparations, sucrosomial iron seems to be a promising new strategy of iron replacement in CD patients.

NCT ID: NCT02912416 Completed - Clinical trials for Prevention of Iron Deficiency

Efficacy of Probiotics on Iron Status During Pregnancy

Start date: September 9, 2016
Phase: N/A
Study type: Interventional

Determine the effect of probiotics on improving iron status in a population of healthy, pregnant women.

NCT ID: NCT02905981 Terminated - Clinical trials for Iron-Refractory Iron-Deficiency Anemia

Triferic IRIDA (Iron-Refractory Iron-Deficiency Anemia) Protocol

Start date: January 17, 2017
Phase: Phase 2
Study type: Interventional

The main purpose is to determine whether Triferic, administered orally with Shohl's solution, is safe and effective for the treatment of iron-refractory iron-deficiency anemia (IRIDA).