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Anemia, Iron Deficiency clinical trials

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NCT ID: NCT02965209 Completed - Clinical trials for Gastrointestinal Hemorrhage

European Novel Motorized Spiral Endoscopy Trial

ENMSET
Start date: November 2015
Phase: N/A
Study type: Interventional

The subject Novel Motorized Spiral Enteroscope (NMSE) represents a new technology which offers all of the advantageous options of spiral enteroscopy with a faster and less invasive approach. The system is similar to other currently marketed endoscopes in that it incorporates a flexible insertion tube, light source, digital imaging, and channels for passing accessories for sample collection or therapeutic interventions. The NMSE system is unique in that it incorporates a user-controlled motor contained in the endoscope's handle to rotate a spiral cuff located on the endoscope's insertion tube. Rotation of this cuff, which has soft spiral-shaped "fins", pleats the small bowel on to the endoscope's insertion tube, thereby allowing rapid and atraumatic access deep into the small bowel. The system also includes a display monitor, a motor control unit, device to display measured motor current and signal torque, and a set of foot pedals. Motorization of the Spiral Enteroscope and limitation of rotation to a short cuff instead of a long overtube promise to accelerate the procedure, to facilitate insertion and to improve maneuvering the instrument in comparison to conventional spiral enteroscopy

NCT ID: NCT02962648 Completed - Clinical trials for Iron Deficiency Anemia

An Extension Trial to Assess the Safety of Re-dosing of Iron Isomaltoside/Ferric Derisomaltose (Monofer®/Monoferric®)

FERWON-EXT
Start date: January 9, 2017
Phase: Phase 3
Study type: Interventional

Evaluate safety and efficacy of intravenous (IV) iron isomaltoside/ferric derisomaltose re-dosing, in subjects who were previously treated with iron isomaltoside/ferric derisomaltose.

NCT ID: NCT02941081 Completed - Clinical trials for Iron Deficiency, Anaemia in Children

A Novel Nano-iron Supplement to Safely Combat Iron Deficiency and Anaemia in Young Children: a Doubleblind Randomised Controlled Trial

IHAT-Gut
Start date: January 8, 2018
Phase: Phase 2
Study type: Interventional

This study aims to determine whether IHAT is non-inferior to ferrous sulphate at correcting iron deficiency and anaemia, and if IHAT does not increase diarrhoea risk in young children living in rural and resource-poor areas of the Gambia. The study hypothesis is that IHAT will eliminate iron deficiency and improve haemoglobin levels in young children without increasing infectious diarrhoea or promoting inflammation in the gut.

NCT ID: NCT02940886 Completed - Clinical trials for Iron Deficiency Anemia

Iron Isomaltoside/Ferric Derisomaltose vs Iron Sucrose for the Treatment of Iron Deficiency Anemia (IDA)

Start date: November 8, 2016
Phase: Phase 3
Study type: Interventional

Evaluate safety and efficacy of iron isomaltoside/ferric derisomaltose (Monofer®/Monoferric®) compared with iron sucrose (Venofer®), in subjects diagnosed with IDA.

NCT ID: NCT02940860 Completed - Clinical trials for Chronic Kidney Disease

Iron Isomaltoside/Ferric Derisomaltose vs Iron Sucrose for Treatment of Iron Deficiency Anemia in Non-Dialysis-Dependent Chronic Kidney Disease

Start date: November 29, 2016
Phase: Phase 3
Study type: Interventional

Evaluation of safety and efficacy of iron isomaltoside/ferric derisomaltose compared with iron sucrose, in subjects with both non-dialysis-dependent chronic kidney disease (NDD-CKD) and iron deficiency anaemia (IDA).

NCT ID: NCT02937454 Completed - Heart Failure Clinical Trials

Study to Compare Ferric Carboxymaltose With Placebo in Patients With Acute Heart Failure and Iron Deficiency

Affirm-AHF
Start date: April 3, 2017
Phase: Phase 4
Study type: Interventional

Study to Compare Ferric Carboxymaltose With Placebo in Patients With Acute Heart Failure and Iron Deficiency (Affirm-AHF)

NCT ID: NCT02912416 Completed - Clinical trials for Prevention of Iron Deficiency

Efficacy of Probiotics on Iron Status During Pregnancy

Start date: September 9, 2016
Phase: N/A
Study type: Interventional

Determine the effect of probiotics on improving iron status in a population of healthy, pregnant women.

NCT ID: NCT02905539 Completed - Clinical trials for Anemia, Iron-Deficiency

A Study Comparing the Iron Substitution With the Medicinal Products Ferinject or Monofer

HOMe_aFers_1
Start date: July 2016
Phase: Phase 4
Study type: Interventional

The purpose of this study is to determine to what extend a treatment with the iron compounds Iron Isomaltoside 1000 or Ferric Carboxymaltose is leading to hypophosphatemia and to study the potential clinical impact of hypophosphatemia.

NCT ID: NCT02892461 Completed - Clinical trials for Anemia, Iron-Deficiency

Effect of Umbilical Cord Milking on Iron Related Health Outcomes for Cesarean-Delivered Infants

Start date: July 2016
Phase: N/A
Study type: Interventional

This study aims to determine whether umbilical cord milking can improve iron related health outcomes for cesarean-delivered infants. Half of participants will receive umbilical cord milking, while the other half will receive routine clinical treatment and care.

NCT ID: NCT02889133 Completed - Iron Deficiency Clinical Trials

Donor Iron Deficiency Study - Red Blood Cells From Iron-deficient Donors: Recovery and Storage Quality

DIDS
Start date: January 2017
Phase: N/A
Study type: Interventional

Primary Hypothesis - The 24-hour post-transfusion RBC recovery of units obtained from donors exhibiting iron-deficient erythropoiesis will not meet FDA standards for clinical use. - The 24-hour post-transfusion RBC recovery of units obtained after intravenous iron repletion will improve significantly and will meet FDA standards for clinical use.