Association of Cognition With Functional Mobility in People With Alzheimer's Disease

Alzheimer's Disease Clinical Trial

Official title:

Association of Cognition With Functional Mobility in People With Alzheimer's Disease

Clinical Trial Details — Status: Not yet recruiting

Administrative data

• NCT number: NCT05113732
• Other study ID #: IUC-PT
• Status: Not yet recruiting
• Start date: November 1, 2021
• Est. completion date: May 1, 2022

Study information

• Verified date: October 2021
• Source: Istanbul University-Cerrahpasa
• Contact: Kübra Nur Menengiç, MSc
• Phone: +90 05054400987
• Email: kmenengic[@]gmail.com
• Is FDA regulated: No
• Study type: Observational [Patient Registry]

Clinical Trial Summary

This study aimed to investigate relationship between cognitive function and functional mobility in Alzheimer's disease.

Description:

Our hypothesis is that the decrease in cognitive function in individuals with Alzheimer's disease is associated with the level of functional mobility. Sociodemographic information of participants will be recorded. Cognition will assessed with Montreal Cognitive Assessment (MoCA), global score and MoCA's visuospatial executive functions, naming, attention, language, abstract thinking, delayed recall, orientation sub-scores will recorded. Functional mobility will assessed Timed Up and Go Test and 5 Times Sit&Stand Test.

Recruitment information / eligibility

• Status: Not yet recruiting
• Enrollment: 64
• Est. completion date: May 1, 2022
• Est. primary completion date: January 1, 2022
• Accepts healthy volunteers: No
• Gender: All
• Age group: N/A and older

Eligibility

Inclusion Criteria:

• Diagnosed with Alzheimer's disease according to the National Institute of --Neurological and Communicative Disorders and Stroke and the Alzheimer's Disease (NINCDS-ADRDA) criteria,
• Over 65 years old,
• Cases who could understand the instructions given in Turkish were included in the study,
• Having ambulation skill independently or with walking aid.

Exclusion Criteria:

• Dementia with Lewy bodies, frontotemporal dementia and one of the other types of dementia,
• Having a pulmonary, neurological, musculoskeletal or rheumatological disease that may prevent exercise,
• Unstable medical condition (uncontrolled diabetes or hypertension, deep vein thrombosis, etc.),
• Subjects with visual or auditory deficits or behavioral problems that would make communication difficult were not included in the study.

Related Conditions & MeSH terms

• Alzheimer Dementia
• Alzheimer Disease
• Alzheimer's Disease
• Dementia
• Dementia, Alzheimer Type

Locations

Country	Name	City	State
Turkey	Istanbul University-Cerrahpasa	Istanbul

Sponsors (1)

Lead Sponsor	Collaborator
Istanbul University-Cerrahpasa

Country where clinical trial is conducted

Turkey, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Montreal Cognitive Assesment (MoCA)	MoCA assesses cognitive skills such as visuospatial / executive functioning, object naming, memory, attention, language, abstraction, orientation. Higher scores reflect the better performance.	Baseline
Primary	Timed Up and Go Test	Timed Up and Go Test measures the level of functional mobility skills and, assess fall risk and balance. The time elapsed between standing up from the sitting position, walking the distance of 3 meters, coming back and sitting back on the chair is recorded. The shorter time reflect the better performance.	Baseline
Primary	5 Time Sit to Stand Test	5 Time Sit to Stand Test measures the level of functional mobility skills and, assess fall risk and lower extremity strength. The test measures the time taken to stand five times from a sitting position as quickly as possible. The shorter time reflect the better performance.	Baseline