Alzheimer's Disease Clinical Trial
Official title:
Mirtazapine for the Treatment of Sleep Disorders in Alzheimer's Disease: a Randomized, Double-blind, Placebo-controlled Study
The purpose of this study is to determine whether mirtazapine is effective in the treatment of sleep disorders in Alzheimers disease.
Mirtazapine has been used for depressed elderly with sleep disorders with good tolerability
and efficacy. The study hypothesis is that mirtazapine could also be used in demented with
sleep disorders.
Sleep disorders (SD) affects 35 to 50 percent of patients with Alzheimer Disease (AD). These
disorders often make caring for patients at home very difficult and It's also associated
with higher risk of institutionalization and increases health care costs. Treatment of SD in
people with dementia may benefit both patients and their caregivers. However, little is
known about the efficacy of pharmacological treatments for treating sleep disturbances in
AD.
;
Allocation: Randomized, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Parallel Assignment, Masking: Double Blind (Subject, Caregiver, Investigator, Outcomes Assessor), Primary Purpose: Treatment
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