SCGs as a Proxy for Determining the Cognitive Status of Older Adults

Alzheimer Disease Clinical Trial

Official title:

Serious Computer Games as a Proxy for Determining the Cognitive Status of Older Adults

Clinical Trial Details — Status: Not yet recruiting

Administrative data

• NCT number: NCT06367231
• Other study ID #: Pro00134554
• Status: Not yet recruiting
• Start date: May 1, 2024
• Est. completion date: July 1, 2025

Study information

• Verified date: April 2024
• Source: University of Alberta
• Contact: Adriana M Rios Rincon, PhD, R.OT
• Phone: 780-492-1728
• Email: aros[@]ualberta.ca
• Is FDA regulated: No
• Study type: Observational

Clinical Trial Summary

Detecting memory problems early is crucial for treating conditions like Mild Cognitive Impairment (MCI), which often leads to dementia. Currently, doctors use tests in clinics to check for these issues. However, there's a growing need for better methods to monitor our cognitive skills over time. Computer games emerge as a cost-effective solution for assessing the brain functions of older adults. In our study, we are investigating the potential of computer games to reflect the cognitive skills of older adults. We developed the VibrantMinds platform, featuring five games: Whack-a-Mole, Bejeweled, Mahjong Solitaire, Word Search, and Memory Game. We have evaluated these games for ease of use, enjoyment, and their impact on brain functions. Now, our goal is to determine whether these games can offer valuable insights into the cognitive skills of older adults. We are collecting demographic data, game-playing data, and cognitive test results. Our analysis will determine the correlation between game data, cognitive test outcomes, and demographic information. Additionally, we will assess both the perceived and observed engagement of older adults as they play the games.

Recruitment information / eligibility

• Status: Not yet recruiting
• Enrollment: 58
• Est. completion date: July 1, 2025
• Est. primary completion date: May 1, 2025
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: All
• Age group: 65 Years and older

Eligibility

Inclusion Criteria:

• Reside in Calgary and/or Edmonton, Alberta, Canada
• sufficient English language skills to converse in English with research staff

Exclusion Criteria:

• Moderate or severe limitations in the control or movement of the upper extremity (e.g., severe arthritis, amyotrophic lateral sclerosis, multiple sclerosis)
• Visual and hearing impairments
• Attention deficit

Related Conditions & MeSH terms

• Alzheimer Disease
• Cognitive Decline
• Cognitive Dysfunction
• Dementia
• Healthy Aging
• Mild Cognitive Impairment

Intervention

Other:
• VibrantMinds
We are exploring the potential of computer games to reveal insights into the cognitive abilities of older adults. We developed the VibrantMinds (https://vibrant-minds.org/vibrantminds2/start) platform, featuring five games: Whack-a-Mole, Bejeweled, Mahjong Solitaire, Word Search, and Memory Game. Our evaluation focused on the usability of these games, their appeal to users, and their effectiveness in enhancing cognitive functions. The next phase of our study aims to determine whether these games can offer meaningful data on the cognitive skills of older adults.

Locations

Country	Name	City	State
n/a

Sponsors (1)

Lead Sponsor	Collaborator
University of Alberta

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Cognition - Global	The Montreal Cognitive Assessment (MoCA) is a brief 30-point test used to screen for cognitive dysfunction in areas including memory, language, visuospatial skills, executive functions, attention, concentration, and orientation. A score of 26 or above is considered normal. Lower scores suggest potential cognitive impairment.	At each session (3 sessions total, once per week, one week apart)
Secondary	Cognition - Global	The Mini-Mental State Examination (MMSE) is a widely used 30-point questionnaire that assesses cognitive function, including orientation, recall, attention, calculation, language, and basic motor skills. A score of 24 or above typically indicates normal cognitive function, while lower scores suggest possible impairment.	At each session (3 sessions total, once per week, one week apart)
Secondary	Cognition - Executive Function	Trail Making Test, Part A and B. The norms and average completion times for the Trail Making Test (TMT) Parts A and B can vary significantly based on age, education, and the specific population being tested. However, general guidelines can provide some insight: TMT Part A: Average completion times for adults can range from 20 to 40 seconds. Younger adults and those with higher levels of education tend to complete Part A more quickly. Completion times increase with age.; TMT Part B: This part is more complex and typically takes longer to complete, with average times ranging from 50 to 120 seconds.	At each session (3 sessions total, once per week, one week apart)
Secondary	Game Performance	Level, Accuracy, Time	Obtained during each game (game played at each session, once per week, one week apart)
Secondary	Game Engagement	Self-reported questionnaire of engagement and engagement indicators	At each session (3 sessions total, once per week, one week apart)

External Links

•   VibrantMinds Platform