Alzheimer Disease Clinical Trial
Official title:
Comparisons of gaIt aNalyses pERformance Between the Gaitrite walkwaYs
The GAITRite® system is an instrumented with resistive pressure sensors gait analyzer. It was
first validate in 2001 against paper-and-pencil (intraclass correlation coefficient [ICC] >
95%) for spatial measures and against video-based (ICC > 93%) for temporal measures, and was
thus a reliable tools to measure step lengths and times in both walkway center and
left-of-center measurements. It was considered as one of the gold standards in gait analyses.
This gait analyze system may distinguish prospectively faller and non-faller older adults,
but it can detect spatial, temporal, and spatiotemporal measures of gait and greater
variability of gait parameters which were associated with and predictive of both global- and
domain-specific cognitive decline. Moreover, spatiotemporal gait parameters analyzed using
GAITRite® were more disturbed in the advanced stages of dementia, and more affected in the
non-AD dementia than in AD suggesting that quantitative gait parameters could be used as a
surrogate marker for improving the diagnosis of dementia.
Nevertheless, GAITRite® is not a unique system and it comprises different walkways. One of
these technologies was a roll-up system (platinum plus classic, RE, Basic and Safari), and
the other was a system composed by a changeable association of plates (CIRFACE). In order to
ensure a good comparability between studies using these different walkways, it appears
important to compare the performances of these walkways in gait analysis. Thus, the main aim
of this study was to compare the performances in gait analyze between the GAITRite® platinum
plus classic and the GAITRite® CIRFACE among older adults. Secondary aims were to compare
these parameters among patients with cognitive complaint, minor or major neurocognitive
disorder (NCD) related to Alzheimer disease.
n/a
| Status | Clinical Trial | Phase | |
|---|---|---|---|
| Completed |
NCT04079803 -
PTI-125 for Mild-to-moderate Alzheimer's Disease Patients
|
Phase 2 | |
| Completed |
NCT04044495 -
Sleep, Rhythms and Risk of Alzheimer's Disease
|
N/A | |
| Terminated |
NCT03052712 -
Validation and Standardization of a Battery Evaluation of the Socio-emotional Functions in Various Neurological Pathologies
|
N/A | |
| Recruiting |
NCT04520698 -
Utilizing Palliative Leaders In Facilities to Transform Care for Alzheimer's Disease
|
N/A | |
| Active, not recruiting |
NCT04606420 -
Can Lifestyle Changes Reverse Early-Stage Alzheimer's Disease
|
N/A | |
| Recruiting |
NCT05820919 -
Enhancing Sleep Quality for Nursing Home Residents With Dementia - R33 Phase
|
N/A | |
| Terminated |
NCT03672474 -
REGEnLIFE RGn530 - Feasibility Pilot
|
N/A | |
| Completed |
NCT03430648 -
Is Tau Protein Linked to Mobility Function?
|
||
| Recruiting |
NCT05557409 -
A Study to Assess the Efficacy and Safety of AXS-05 in Subjects With Alzheimer's Disease Agitation
|
Phase 3 | |
| Recruiting |
NCT04522739 -
Spironolactone Safety in African Americans With Mild Cognitive Impairment and Early Alzheimer's Disease
|
Phase 4 | |
| Recruiting |
NCT05288842 -
Tanycytes in Alzheimer's Disease and Frontotemporal Dementia
|
||
| Recruiting |
NCT04949750 -
Efficacy of Paper-based Cognitive Training in Vietnamese Patients With Early Alzheimer's Disease
|
N/A | |
| Completed |
NCT06194552 -
A Multiple Dose Study of the Safety and Pharmacokinetics of NTRX-07
|
Phase 1 | |
| Completed |
NCT03239561 -
Evaluation of Tau Protein in the Brain of Participants With Alzheimer's Disease Compared to Healthy Participants
|
Early Phase 1 | |
| Completed |
NCT03184467 -
Clinical Trial to Evaluate the Efficacy and Safety of GV1001 in Alzheimer Patients
|
Phase 2 | |
| Active, not recruiting |
NCT03676881 -
Longitudinal Validation of a Computerized Cognitive Battery (Cognigram) in the Diagnosis of Mild Cognitive Impairment and Alzheimer's Disease
|
||
| Terminated |
NCT03487380 -
Taxonomic and Functional Composition of the Intestinal Microbiome: a Predictor of Rapid Cognitive Decline in Patients With Alzheimer's Disease
|
N/A | |
| Completed |
NCT05538455 -
Investigating ProCare4Life Impact on Quality of Life of Elderly Subjects With Neurodegenerative Diseases
|
N/A | |
| Recruiting |
NCT05328115 -
A Study on the Safety, Tolerability and Immunogenicity of ALZ-101 in Participants With Early Alzheimer's Disease
|
Phase 1 | |
| Completed |
NCT05562583 -
SAGE-LEAF: Reducing Burden in Alzheimer's Disease Caregivers Through Positive Emotion Regulation and Virtual Support
|
N/A |