Alveolar Bone Loss Clinical Trial
Official title:
Periapical Bone Healing After Apicectomy With and Without Retrograde Root Filling
Ph.D project: Periapical bone healing after apicectomy with and without retrograde root
filling.
The aim of this study is to assess periapical bone healing after apicectomy without a
filling and apicectomy combined with a retrograde filling material, MTA. Further, we will
estimate risk factors in non-healing cases.
Study hypothesis: There is no difference in treatment outcome between:
Periapical bone healing after apicectomy with retrograde root filling and Periapical bone
healing after apicectomy without retrograde root filling
Ph.D project: Periapical bone healing after apicectomy with and without retrograde root
filling.
60 patients have been selected from a group of 490 patients, who had a full mouth
radiographic status taken in connection with a population study of apical periodontitis in
Aarhus Community. The selection criteria for the 60 patients were patients with a persisting
apical periodontitis, Periapical Index (PAI) score 3-5, on front teeth and premolars in the
upper jaw. The orthograde root filling in the tooth must be at least 2 years old and
sufficient regarding density and length.
The 60 patients will be randomised into the two groups of apicectomy with and without
filling. A radiograph will be taken just before the operation and 6 and 12 months after the
operation. In the assessment of bone healing, we will use two different techniques,
subtraction radiography and the Periapical Index (PAI).
We will also evaluate the benefits of using the operation microscope during the operation,
and if clinical photos can be useful as documentation of treatment result.
;
Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Open Label, Primary Purpose: Treatment
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