Clinical Trials Logo
  1. Home
  2. Altitude Hypoxia
  3. NCT05468515

Reference Interval for SPO2 in Neonates at High Altitudes During First 2 Hours and Umbilical Artery Blood Gas

Neonatal Disease Clinical Trial

Official title:
Reference Interval for Pulse Oxygen Saturation in Neonates at High Altitudes During First 2 Hours and Umbilical Artery Blood Gas: a Multicenter Prospective Study

Clinical Trial Summary

Pulse oximetry offers real time and non-invasive estimation of arterial oxygen saturation in a cost-effective way, and has become a critical tool in guiding the usage of supplemental oxygen in sick newborns. During postnatal transition, pulmonary pressure decreases upon the activation of the lungs, and the ductus arteriosus constricts and closes upon the increase of partial oxygen pressure, which is negatively correlated with altitude. As a result, postnatal transition may be different at high altitudes. Umbilical cord blood gas analysis is now recommended in all high-risk deliveries because of its' value in providing information about preceding fetal hypoxic stress. But there are only limited studies about the SpO2 measurements during the first few hours after birth and umbilical blood gas analysis at high altitudes, especially at altitudes above 2500m. The primary outcome of the study is to determine the reference intervals for preductal oxygen saturation during first 2 hours of life stratified by different gestational age. The secondary outcomes is to establish the pH and lactate cutoff value of umbilical arterial blood gas at different altitude level.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT05468515
Study type Observational
Source Children's Hospital of Fudan University
Contact
Status Completed
Phase
Start date March 15, 2022
Completion date February 27, 2023
View Details
See also
  Status Clinical Trial Phase
Completed NCT04746885 - Effect of DHA on Proinflammatory Cytokines Including Platelets Activating Factor (PAF) in Preterm Neonates N/A
Completed NCT06015828 - Effect of Enteral Bovine Lactoferrin in Preterm Infants N/A
Completed NCT05152316 - The Baby Lung Study
Recruiting NCT04920175 - Real-time State of Vigilance Monitor for the Neonatal Intensive Care Unit
Recruiting NCT04074824 - A Genome-Wide Association Study for Neonatal Diseases
Completed NCT04366102 - Reducing Pain and Promoting Neurodevelopment Among Preterm Neonates N/A
Recruiting NCT06087315 - Evaluation of a Multi-country Medical Oxygen Program
Recruiting NCT06206590 - Analysis of Differential Proteins and Maternal Influencing Factors of Septic Shock in Neonates
Active, not recruiting NCT06458699 - Management Of Stoma In Patients Younger Than 3 Months Old
Recruiting NCT05896306 - Cerebral Monitoring Using Pulsatile Near Infrared Spectroscopy in Neonates
Recruiting NCT06408064 - The Effect of Music Therapy as an Adjuvant in the Vital Signs of the Neonate N/A
Recruiting NCT06408480 - Neonatologist-performed Lung Ultrasound in the Delivery Room
Active, not recruiting NCT06461325 - Surgical Management Of Gastroschisis
Completed NCT05880433 - The Effects of Mydriatic Eye Drops in Retinopathy of Prematurity Examinations
Recruiting NCT04401540 - Characteristics of Neonatal Covid-19 in Turkey
Enrolling by invitation NCT05565287 - Neonatal Neurobehavioral And Motor Behavior In Ultra Early Physical Therapy Intervention N/A
Not yet recruiting NCT06263790 - Intubating Laryngeal Mask vs Direct Laryngoscopy: a Crossover Randomized Controlled Preterm Manikin Trial N/A
Completed NCT05860166 - Development of a Scale for Evaluation of Neuromotor Development of Infants N/A
Active, not recruiting NCT05762835 - Neonatal Intensive Care Unit Virtual Family-Centered Rounds N/A
Recruiting NCT06258187 - Pedi-Cap CO2 Detector for Face-mask Ventilation in the Delivery Room N/A