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Completed
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Microbioma in Sputa From COPD With Alpha-1 Antitrypsin Deficiency
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Completed
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Ex-vivo Perfusion and Ventilation of Lungs Recovered From Non-Heart-Beating Donors to Assess Transplant Suitability
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N/A |
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Completed
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Alpha1-antitrypsin Deficiency Registry
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N/A |
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Withdrawn
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Safety, Tolerability and Effect of ARC-AAT Injection on Circulating and Intrahepatic Alpha-1 Antitrypsin Levels
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Phase 2 |
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Terminated
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Environment Effect on Six-Minute Walk Test Performance
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N/A |
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Completed
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Liver Fibrosis in Alpha-1 Antitrypsin Deficiency (Liver AATD)
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Active, not recruiting
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Respreeza® Self-administration and Learning Program (AmAREtTI Study)
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Recruiting
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A Phase 1 Research Study to Evaluate Safety, Tolerability, and Pharmacokinetics of WVE-006 in Healthy Participants With Wild-type AAT Expression (RestorAATion-1)
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Phase 1 |
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Not yet recruiting
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A Phase 1b/2a, Open-label Single Ascending Doses and Multiple Ascending Doses Study in Participants With Pi*ZZ AATD
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Phase 1/Phase 2 |
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Completed
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Safety & Efficacy Study of rAAV1-CB-hAAT for Alpha-1 Antitrypsin Deficiency
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Phase 2 |
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Completed
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Phase 1 Study to Assess the Safety, PK and PD of INBRX-101 in Adults With Alpha-1 Antitrypsin Deficiency
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Phase 1 |
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Completed
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Targeting Pulmonary Perfusion in Alpha-1 Antitrypsin Deficiency
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Phase 2 |
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Completed
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Prevalence of Alpha-1 Antitrypsin Deficiency in Chronic Obstructive Pulmonary Disease (COPD)
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N/A |
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Recruiting
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The Alpha-1 Foundation's and University of Florida's Alpha-1 Coded Testing (ACT) Study
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Active, not recruiting
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A Study to Evaluate Efficacy and Safety of VX-864 in Participants With the PiZZ Genotype
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Phase 2 |
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Completed
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Alpha-1 Carrier Genomics Study
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Terminated
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A Study of ARC-AAT in Healthy Volunteer Subjects and Patients With Alpha-1 Antitrypsin Deficiency (AATD)
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Phase 1 |
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Completed
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Long-Term Follow-up Study of ADVM-043
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Active, not recruiting
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Alpha-1 Antitrypsin Deficiency Adult Liver Study
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Terminated
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Phase 2 Study of Ex-vivo Perfusion and Ventilation of Lungs to Assess Transplant Suitability
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N/A |