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Microbiota and Allergy — MATFA I  

Allergy Clinical Trial

Official title:
Microbiota as Potential Target for Innovative Preventive and Therapeutic Strategies for Food Allergy

Clinical Trial Summary

Food allergy derives from a dysregulation of oral tolerance mechanisms. Studies suggest a crucial role for gut microbiota in oral tolerance development. An altered composition of gut microbiota results in an unbalanced local and systemic immune response to food allergens. There are qualitative and quantitative differences in gut microbiota composition in children with food allergy. Preliminary results of MATFA study demonstrated gut microbiota in allergic children.These findings support the pivotal role of the gut microbiota in the pathogenesis of allergic diseases and may open new strategies in the development of innovative preventive and therapeutic approaches.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT04750980
Study type Observational
Source Federico II University
Contact
Status Completed
Phase
Start date June 1, 2017
Completion date January 30, 2021
View Details
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