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Allergy clinical trials

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NCT ID: NCT00339573 Completed - Asthma Clinical Trials

National Survey of Lead and Allergen Hazards in Housing

Start date: June 30, 1998
Phase:
Study type: Observational

We propose to conduct a scientifically valid, descriptive survey to measure the prevalence and levels of lead in dust, soil, and paint, and the prevalence and levels of various indoor allergens in floor and bedding dust in the nation's housing stock. The survey strategy is a population-based, multi-stage area probability sample designed to represent all 50 states. The survey will include approximately 1000 homes in at least 100 primary sampling units (PSU, a metropolitan area or cluster of counties). Residents of candidate participant housing units (HUs) will initially be contacted by a letter to introduce and provide a brief explanation of the study. A field interviewer will then visit each candidate HU to screen and recruit eligible units into the study. A short Screening Questionnaire will be administered to an adult HU resident and an invitation will be extended to those HUs that are eligible to participate in the study. A field data collection visit will be scheduled for the following week, at the resident's convenience. The collection visit will be conducted by two member team (including the same field interviewer that will conduct the screening/recruiting visit) and will consist of administration of an informed consent form and Data Collection Questionnaire, completion of home observation forms, collection of interior dust and exterior soil samples, and conduct of nondestructive paint lead analysis on both interior and exterior walls. Soil and dust samples will be shipped to analytical laboratories for lead and allergen analysis. Extensive survey design, procedure, and reporting details are provided in the National Survey Lead Hazards and Allergens in Housing: Protocol and Sample Design Report (Attachment A). It is anticipated that this study will provide allergen-specific data regarding: 1) housing conditions, demographic factors, and climate to facilitate evaluation of regional, ethnic, socioeconomic, and housing characteristic differences in the indoor allergen burden; 2) an estimate of indoor allergen exposure in the U.S. population; 3) baseline data that can be used to stimulate future studies which attempt to correlate allergen exposure to disease outcome. The study will yield lead hazard data to: 1) estimate the number and percent of homes with dust and soil lead levels above selected thresholds; 2) identify sources of lead in dust in housing; 3) permit future analysis of lead hazard control strategies an costs, including associated policy and regulatory guidelines.

NCT ID: NCT00331929 Completed - Allergy Clinical Trials

Respiratory Health Study of Children in Kiryat Tivon

Start date: September 2006
Phase: N/A
Study type: Interventional

Kiryat Tivon is located close to a major industrial zone. The aim of the study is to evaluate the health status of children living in K. Tivon. The health status will be evaluated using health questionnaires and spirometry.

NCT ID: NCT00330083 Completed - Allergy Clinical Trials

Safety of ALK Ragweed Tablet

Start date: May 2006
Phase: Phase 1
Study type: Interventional

This trial is performed to assess whether ALK Ragweed Tablet is safe to use in adults

NCT ID: NCT00318747 Terminated - Asthma Clinical Trials

Treatment of Ragweed-Allergic Asthma With an Immunostimulatory Drug

Start date: April 2006
Phase: Phase 2
Study type: Interventional

This study will test the effectiveness of an investigational treatment for patients with ragweed-induced asthma, sometimes called fall seasonal asthma. The treatment being tested is a series of anti-ragweed shots. The purpose of the study is to determine whether a short series of injections with Amb a 1-immunostimulatory oligodeoxyribonucleotide conjugate (AIC) can cause a long-lasting reduction in the symptoms of asthma that are caused by fall hay fever allergies.

NCT ID: NCT00310466 Completed - Allergy Clinical Trials

Efficacy and Safety Trial of SLITone(TM) Birch in Subjects With Hayfever

Start date: June 2005
Phase: Phase 3
Study type: Interventional

The trial is performed to assess the efficacy and safety of SLIT One birch for treatment of birch pollen induced allergy

NCT ID: NCT00310453 Completed - Allergy Clinical Trials

Tolerability of ALK Grass Tablet in Children

Start date: March 2006
Phase: Phase 1
Study type: Interventional

The purpose of this trial is to assess whether the ALK Grass tablet treatment is safe to use in children aged 5-12 years

NCT ID: NCT00309036 Completed - Allergy Clinical Trials

Safety and Efficacy of Recombinant Grass Pollen Allergen Cocktail in the Treatment of Allergic Rhinoconjunctivitis

Start date: January 2004
Phase: Phase 3
Study type: Interventional

The trial is performed to assess efficacy and safety of a recombinant grass Pollen allergen cocktail in allergic rhinoconjunctivitis

NCT ID: NCT00298701 Completed - Allergy Clinical Trials

Tolerability of Grazax-R in Children

Start date: February 2006
Phase: Phase 1
Study type: Interventional

This trial is performed to assess whether the Grazax-R treatment is safe to use in children aged 5-12 years.

NCT ID: NCT00298519 Completed - Allergy Clinical Trials

Maternal Ethnic Group,Diet,Breast Milk Fatty Acid and Potential Effect Development of Allergy in the Offspring

Start date: June 2003
Phase: N/A
Study type: Observational

Women of different ethnic groups have different diets that may affect the fatty acid content of their breast milk. Ethnicity may also have an independent effect on breast milk composition. The differences in fatty acid content of breast milk may influence the immune tolerance of breastfed babies, and hence the development of allergy.

NCT ID: NCT00293046 Completed - Allergy Clinical Trials

Assessment of Grazax® Treatment Compliance

Start date: February 2006
Phase: Phase 3
Study type: Interventional

This trial is performed to assess whether the Grazax® treatment compliance can be improved by use of a compliance device (Memozax®).