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Allergy clinical trials

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NCT ID: NCT00537342 Completed - Allergy Clinical Trials

Immunotherapy With Depigmented and Polymerized Allergen Extract of Olea Europaea (GPIT)

Start date: October 2007
Phase: Phase 3
Study type: Interventional

The objective of this trial is to evaluate the clinical effectiveness of the administration of a depigmented and polymerized allergen extract of Olea europaea in the rhinitis or allergic rhinoconjunctivitis

NCT ID: NCT00535639 Completed - Allergy Clinical Trials

Tolerability of ALK Tree Tablet

Start date: October 2007
Phase: Phase 1
Study type: Interventional

This trial is performed to assess the tolerability of the ALK Tree Tablet in patients with birch pollen induced allergy

NCT ID: NCT00521170 Completed - Allergy Clinical Trials

Wheal and Flare Reaction During 24 Hours in Allergic Volunteers.

Start date: November 2004
Phase: Phase 1
Study type: Interventional

Compare the activity of 5 mg levocetirizine and 5 mg desloratadine on allergen-induced wheal and flare reaction.

NCT ID: NCT00519740 Completed - Allergy Clinical Trials

Influence of Nutrition on Nasal and Bronchial Affliction in Patients With Allergy on Grass-Pollen

Start date: August 2006
Phase: N/A
Study type: Interventional

The study is meant to observe the influence of nutrition on nasal and bronchial discomfort in patients with allergy on grass pollen after specific bronchial provocation. Therefore, the investigators will record the patients' nutrition habits and measure the blood level of long chained polyunsaturated fatty-acids.

NCT ID: NCT00510432 Recruiting - Allergy Clinical Trials

Incidence and Nature of Heparin-induced Skin Lesions in Medical Patients

Start date: April 2007
Phase: N/A
Study type: Observational

An increased number of patients with heparin-induced skin lesions is reported in the literature. Heparin-induced skin lesions may result from either occlusion of cutaneous vessels in patients suffering from autoimmune HIT or from a type IV allergic reaction (delayed type hypersensitivity (DTH) response). However, the incidence and nature of heparin-induced skin lesions has not been determined in a prospective investigation. To address this open issue is the goal of this ongoing, so far monocenter, clinical investigation.

NCT ID: NCT00461721 Completed - Allergy Clinical Trials

Pilot Trial to Elaborate a Cutaneous Antigen Neutralization Test in Patients Suffering From Rhinoconjunctivitis

Start date: December 2006
Phase: Phase 1
Study type: Observational

To find a test to elaborate a parameter for specific immunotherapy in allergic patients

NCT ID: NCT00448851 Completed - Allergy Clinical Trials

Study of Dust Mite Inhalation in Humans

Start date: February 2007
Phase: Phase 1
Study type: Interventional

The purpose of this research study is to learn more about the effect of inhaled dust mite allergen extract on airway responses in allergic individuals with mild asthma. Information learned from this study will be used to identify a safe dose range of D Farinae extract for use in inhalation challenge studies. This study will also help determine how inhalation of the allergen affects mucociliary clearance (MCC) which is a measure of how quickly mucus clears from the airway.

NCT ID: NCT00439621 Completed - Allergy Clinical Trials

Safety Study of Anti-IgE Immunotherapy in Allergic Patients

Start date: February 2007
Phase: Phase 2
Study type: Interventional

The purpose of the study is to evaluate safety and efficacy of three doses and two dosing regimens of RP01 as an anti-IgE immunotherapy in allergic patients.

NCT ID: NCT00434421 Completed - Asthma Clinical Trials

Sublingual Cockroach Safety in Adults With Cockroach Allergy & Perennial Allergic Rhinitis With or Without Asthma

SCSS
Start date: February 2007
Phase: Phase 1
Study type: Interventional

Immunotherapy may help reduce symptoms of allergy and asthma. Problems concerning compliance and adverse events with subcutaneous allergen immunotherapy have generated interest in delivering immunotherapy sublingually (under the tongue). The purpose of this study is to evaluate the safety of a cockroach extract given sublingually to people with perennial (year-round) allergic rhinitis, with or without asthma.

NCT ID: NCT00429429 Completed - Allergy Clinical Trials

Immunotherapy for Peanut Allergy

Start date: April 2006
Phase: N/A
Study type: Interventional

Currently, when a food allergy is diagnosed, the "standard of care" is strict avoidance of the allergic food and ready access to self-injectable epinephrine. Yet, accidental ingestions do occur. Unfortunately, for a ubiquitous food such as peanut, the possibility of an inadvertent ingestion is great. It is estimated that over 50% of individuals who are allergic to peanuts will have an accidental reaction to peanuts over a 2-year period. The purpose of this study is to determine if peanut sublingual immunotherapy (SLIT) reduces the number and/or symptoms of accidental peanut ingestion in peanut allergic subjects. We would anticipate that the subjects on the peanut SLIT protocol would experience few adverse effects with accidental peanut ingestion over the course of the two years of SLIT. The primary endpoint to evaluate the effectiveness of SLIT will be a negative DBPCFC to peanuts (8 grams) at the completion of the two years of the study.