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Alkalosis, Metabolic clinical trials

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NCT ID: NCT03837886 Not yet recruiting - Fatigue Clinical Trials

Effects of Sodium Bicarbonate Supplementation on Intermittent and Intense Task

Start date: October 20, 2019
Phase: N/A
Study type: Interventional

The aim of this study was to verify if sodium bicarbonate (NaHCO3) suplementation promotes changes in the performance, muscular activity and strength of individuals trained during the intermittent and intense task . Twelve trained adult men will participate in this randomized, double-blind, crossover clinical trial. Each participant should receive two types of intervention with a 14-day interval between conditions: alkalosis (ALK) in which gelatinous capsules containing 0.3 g.kg -1 of NaHCO 3 and placebo (PLA) are administered, in which 0.3 g.kg-1 of Calcium Carbonate (CaCO3). The following results will be considered: electromyographic activity (EMG) of the quadriceps muscle, peak torque, pH, lactate, and perception of effort, recovery and pain questionnaires, which will be collected during intermittent and high intensity DI protocol. ANOVA of repeated measures will be used to verify possible differences between groups.

NCT ID: NCT01131377 Recruiting - Ventilator Weaning Clinical Trials

Acetazolamide Facilitates Ventilator Weaning

Start date: May 2010
Phase: N/A
Study type: Interventional

Metabolic alkalosis(MA) is common metabolic disorder in ICU setting. MA could be cause of weaning failure or delay by depression of respiratory center. The purpose of this study is to evaluate that correction of MA by administration of acetazolamide facilitates weaning of mechanical ventilation.