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Clinical Trial Summary

Oral disulfiram (Antabuse®) has been shown to improve image-forming vision in animal models with retinal degeneration due to its ability to decrease Retinoic Acid synthesis and consequently reduce hyperactivity in the inner retina. The investigator will aim to evaluate the impact of oral disulfiram on the vision of patients with retinal degeneration who are being treated with the drug in the management of their concurrent alcohol use disorder.


Clinical Trial Description

n/a


Study Design


Related Conditions & MeSH terms


NCT number NCT06319872
Study type Interventional
Source University of Rochester
Contact Alicia Papalia
Phone 585-275-2107
Email alicia_papalia@urmc.rochester.edu
Status Not yet recruiting
Phase Phase 1
Start date April 15, 2024
Completion date April 15, 2025

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