Phase 1b Study of DCR-AUD in Healthy Volunteers

Status Completed

Clinical Trial Summary

The goal of this clinical trial is to test the safety, tolerability, pharmacokinetics (PK), and pharmacodynamics (PD) of of repeat doses of DCR-AUD in adult healthy volunteers who are social drinkers. The main questions it aims to answer are: - Are repeat doses of DCR-AUD safe and well-tolerated in healthy adults who are social drinkers? - How does the drug behave inside the human body and how it is removed from the human body? - What are the symptoms the drug may cause with alcohol consumption? Participants will: - Receive multiple doses of DCR-AUD. - Have assessment visits through Week 24. - Participate in up to 10 Ethanol Interaction Assessments (EIAs) to see how the body is affected by DCR-AUD. Researchers will compare the groups of participates who receive study drug with the group of participants who receive placebo to see if the study drug is safe and tolerable and whether the study drug has any real effect.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT05845398
Study type	Interventional
Source	Dicerna Pharmaceuticals, Inc., a Novo Nordisk company
Contact
Status	Completed
Phase	Phase 1
Start date	January 29, 2023
Completion date	August 22, 2023

View Details

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