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Dexamethasone to Target Stress and Immune System Mechanisms Underlying Alcohol Craving

Alcohol Use Disorder Clinical Trial

Official title:
Dexamethasone to Target Stress and Immune System Changes During Early Abstinence in Individuals With Alcohol Use Disorder (AUD)

Clinical Trial Summary

This is a double-blind, placebo-controlled, proof of concept laboratory study to recruit N=70 (35 Males / 35 Females) non-treatment seeking, heavy drinkers with alcohol use disorder (AUD). It is hypothesized that randomization to 1.5mgs dexamethasone versus placebo will decrease alcohol craving during stress by decreasing basal cortisol, increasing anti-inflammatory cytokine levels and potentially normalizing the immune response to stress.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT05305404
Study type Interventional
Source Stony Brook University
Contact Helen C Fox, PhD
Phone 631 638 0057
Email helen.fox@stonybrookmedicine.edu
Status Recruiting
Phase Early Phase 1
Start date March 11, 2022
Completion date June 30, 2024
View Details
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