Clinical Trials Logo
  1. Home
  2. Alcohol Intoxication
  3. NCT04931095

The Impact of Oral Cannabis Administration and Co-Administration of Alcohol on Impairment

Alcohol Intoxication Clinical Trial

Official title:
The Impact of Oral Cannabis Administration and Co-Administration of Alcohol on Impairment

Clinical Trial Summary

This study will evaluate the individual and interactive effects of oral cannabis and alcohol on subjective and behavioral measures of impairment.

Clinical Trial Description

This clinical laboratory study will be double-blind, placebo-controlled and will utilize a within-subjects experimental design. Participants will complete 7 outpatient drug administration sessions that will consist of self-administration of oral cannabis (0, 10 or 25mg THC) and alcohol (either placebo or active; BAC of 0.05 percent); participants will always receive both an alcohol drink (active or placebo) and dose of cannabis (active or placebo). Participants will also complete a condition in which they administer alcohol (BAC: 0.08 percent) with placebo cannabis, as a positive control. Primary outcomes include performance on field sobriety tests, cognitive and psychomotor impairment, subjective drug effects, and simulated driving performance. Blood concentrations of THC and THC metabolites will also be determined. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT04931095
Study type Interventional
Source Johns Hopkins University
Contact Tory Spindle, PhD
Phone 410-550-0529
Email tspindle@jhmi.edu
Status Recruiting
Phase Phase 1
Start date February 17, 2022
Completion date May 1, 2025
View Details
See also
  Status Clinical Trial Phase
Completed NCT04230460 - Cannabis Impairment Detection Application (CIDA) N/A
Terminated NCT04192448 - Men, Mood, and Attention Study: Examination of Alcohol, State Anger, and Emotion Regulation Sexual Aggression N/A
Completed NCT00515294 - Acute and Residual Effects of Caffeinated Beer Phase 2
Recruiting NCT05779774 - WayToServePlus: Improving Responsible Alcohol Service Ph II N/A
Completed NCT03449095 - Understanding Alcohol Reward in Social Context N/A
Completed NCT02861807 - Mindfulness-Based Intervention and Transcranial Direct Current Brain Stimulation to Reduce Heavy Drinking N/A
Completed NCT01783223 - Prevalence of Chronic Inebriates to the Emergency Department and Suitability for Sobering House Services
Completed NCT01688245 - A Text Message Behavioral Intervention to Reduce Alcohol Consumption in Young Adults N/A
Completed NCT05028413 - Evaluating Perceived Fitness to Drive While Intoxicated N/A
Active, not recruiting NCT00608686 - Neurosteroids and Acute Alcohol Intoxication in Humans Phase 1
Recruiting NCT05701865 - Biphasic Effects of Acute Alcohol Intoxication on Bystander Intervention N/A
Recruiting NCT05757089 - Efficacy of the Dietary Food Supplement ALCOFILTRUM in Alleviating Alcohol Hangover Symptoms N/A
Recruiting NCT04912492 - Promoting Prosocial Bystander Behavior in Intoxicated Men: Evaluation of RealConsent2.0 N/A
Not yet recruiting NCT06293040 - Vaporized Cannabis Administration and Co-Administration of Alcohol on Impairment Phase 1
Active, not recruiting NCT04564599 - The Rise of Ride Sharing Companies and Trends in Impaired Driving Accidents
Not yet recruiting NCT04229732 - Trials of Ventilation Assisted Substance Elimination Via the Lung - Ethanol (VASEL - Ethanol) N/A
Recruiting NCT06065657 - Effect of Nutritional Ketosis on Alcohol Metabolism Phase 2/Phase 3
Recruiting NCT03242161 - Development of LabPatch-alcohol as a Noninvasive Skin Patch to Detect Blood Alcohol Concentrations Early Phase 1
Active, not recruiting NCT03467191 - Behavioral Alcohol Responses (BAR) Study Early Phase 1
Recruiting NCT06264791 - Stress-motivated Alcohol Use as a Value-based Decision-making Process N/A