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Clinical Trial Summary

This study will evaluate the individual and interactive effects of oral cannabis and alcohol on subjective and behavioral measures of impairment.


Clinical Trial Description

This clinical laboratory study will be double-blind, placebo-controlled and will utilize a within-subjects experimental design. Participants will complete 7 outpatient drug administration sessions that will consist of self-administration of oral cannabis (0, 10 or 25mg THC) and alcohol (either placebo or active; BAC of 0.05 percent); participants will always receive both an alcohol drink (active or placebo) and dose of cannabis (active or placebo). Participants will also complete a condition in which they administer alcohol (BAC: 0.08 percent) with placebo cannabis, as a positive control. Primary outcomes include performance on field sobriety tests, cognitive and psychomotor impairment, subjective drug effects, and simulated driving performance. Blood concentrations of THC and THC metabolites will also be determined. ;


Study Design


Related Conditions & MeSH terms


NCT number NCT04931095
Study type Interventional
Source Johns Hopkins University
Contact Tory Spindle, PhD
Phone 410-550-0529
Email tspindle@jhmi.edu
Status Recruiting
Phase Phase 1
Start date February 17, 2022
Completion date May 1, 2025

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