Clinical Trials Logo
  1. Home
  2. Alcohol Intoxication
  3. NCT04229732
  4. Details
NCT04229732 Clinical Trial

Trials of Ventilation Assisted Substance Elimination Via the Lung - Ethanol (VASEL - Ethanol)

Alcohol Intoxication Clinical Trial

Official title:
Trials of Ventilation Assisted Substance Elimination Via the Lung - Ethanol (VASEL - Ethanol)

Clinical Trial Details — Status: Not yet recruiting

Administrative data
NCT number NCT04229732
Other study ID # CAPCR ID 15-8982.4
Secondary ID
Status Not yet recruiting
Phase N/A
First received
Last updated
Start date July 2020
Est. completion date July 2022

Study information
Verified date January 2020
Source University Health Network, Toronto
Contact n/a
Is FDA regulated No
Health authority
Study type Interventional

Clinical Trial Summary

This prospective, randomized control trial will use passive, isocapnic hyperventilation, applied via the ClearMateTM device (Thornhill Medical, Inc) versus controls receiving standard of care supportive management for severe alcohol intoxication to assess for enhanced ethanol elimination kinetics.

Recruitment information / eligibility
Status Not yet recruiting
Enrollment 40
Est. completion date July 2022
Est. primary completion date July 2022
Accepts healthy volunteers Accepts Healthy Volunteers
Gender All
Age group 18 Years to 80 Years
Eligibility Inclusion Criteria:

- intoxicated requiring admission to an emergency unit

Exclusion Criteria:

- Liver or renal disease

Study Design

Related Conditions & MeSH terms

Intervention

Device:
• ClearMateTM
Passive isocapnic hyperventilation breathing circuit.

Locations
Country Name City State
n/a

Sponsors (2)
Lead Sponsor Collaborator
University Health Network, Toronto Thornhill Medical

Outcome
Type Measure Description Time frame Safety issue
Primary Alcohol elimination time constant From the recorded venous ethanol blood alcohol values, an elimination time constant will be calculated 6-24 hours
See also
  Status Clinical Trial Phase
Completed NCT04230460 - Cannabis Impairment Detection Application (CIDA) N/A
Terminated NCT04192448 - Men, Mood, and Attention Study: Examination of Alcohol, State Anger, and Emotion Regulation Sexual Aggression N/A
Completed NCT00515294 - Acute and Residual Effects of Caffeinated Beer Phase 2
Recruiting NCT05779774 - WayToServePlus: Improving Responsible Alcohol Service Ph II N/A
Completed NCT03449095 - Understanding Alcohol Reward in Social Context N/A
Completed NCT02861807 - Mindfulness-Based Intervention and Transcranial Direct Current Brain Stimulation to Reduce Heavy Drinking N/A
Completed NCT01688245 - A Text Message Behavioral Intervention to Reduce Alcohol Consumption in Young Adults N/A
Completed NCT01783223 - Prevalence of Chronic Inebriates to the Emergency Department and Suitability for Sobering House Services
Completed NCT05028413 - Evaluating Perceived Fitness to Drive While Intoxicated N/A
Not yet recruiting NCT06419647 - Tracking Mood: The Effects of Daily Mood Tracking VAS on Alcohol Consumption in Adult Heavy Drinkers N/A
Active, not recruiting NCT00608686 - Neurosteroids and Acute Alcohol Intoxication in Humans Phase 1
Recruiting NCT05701865 - Biphasic Effects of Acute Alcohol Intoxication on Bystander Intervention N/A
Recruiting NCT05757089 - Efficacy of the Dietary Food Supplement ALCOFILTRUM in Alleviating Alcohol Hangover Symptoms N/A
Recruiting NCT04912492 - Promoting Prosocial Bystander Behavior in Intoxicated Men: Evaluation of RealConsent2.0 N/A
Active, not recruiting NCT04564599 - The Rise of Ride Sharing Companies and Trends in Impaired Driving Accidents
Recruiting NCT06065657 - Effect of Nutritional Ketosis on Alcohol Metabolism Phase 2/Phase 3
Recruiting NCT03242161 - Development of LabPatch-alcohol as a Noninvasive Skin Patch to Detect Blood Alcohol Concentrations Early Phase 1
Recruiting NCT04931095 - The Impact of Oral Cannabis Administration and Co-Administration of Alcohol on Impairment Phase 1
Active, not recruiting NCT03467191 - Behavioral Alcohol Responses (BAR) Study Early Phase 1
Recruiting NCT06264791 - Stress-motivated Alcohol Use as a Value-based Decision-making Process N/A