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Naltrexone and Memantine Effects on Alcohol Drinking Behaviors

Alcohol Drinking Clinical Trial

Official title:
Glutamate-opioid Interactions in Alcohol Drinking Behaviors

Clinical Trial Summary

The purpose of this study is to evaluate the combined effects of the study medications naltrexone and memantine on alcohol drinking behaviors.

Clinical Trial Description

Participants will be randomized to receive a combination of naltrexone/memantine over a one week period and then participate in a laboratory session. During this session, participants are given an initial drink of alcohol followed by the choice to drink up to 12 more drinks over a three-hour period. These medications are hypothesized to reduce craving and number of drinks consumed prior to and after exposure to the initial drink of alcohol and during the three hour drinking period. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT01519063
Study type Interventional
Source Yale University
Contact
Status Completed
Phase Phase 2
Start date January 2012
Completion date May 1, 2017
View Details
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