Alcohol Dependence Clinical Trial
Official title:
The Neural Mechanisms of the Incubation of Cue-induced Craving in Alcohol Dependence
In order to determine whether the 'incubation of craving' phenomenon also occurred in alcoholics, investigators employed an experimental approach to investigate the time course of cue-induced craving in alcoholism. Eighty male participants were randomly divided into Four groups, and they were assessed at 7, 14, 30, and 60 days of abstinence for cue-induced alcohol craving . Another group including 19 patients was repeatedly tested for the cue-induced alcohol craving at the above abstinence days. Other psychological and physiological measures were administered at the four abstinence time points.
All subjects provided written informed consent after a full explanation of the protocol design. ;
Observational Model: Case-Only, Time Perspective: Prospective
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