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Alcohol Consumption clinical trials

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NCT ID: NCT06136195 Not yet recruiting - Alcohol Consumption Clinical Trials

Influence of Mavoglurant on Alcohol Craving and Drinking in Heavy Drinkers

Start date: July 1, 2024
Phase: Phase 2
Study type: Interventional

The purpose of this research study is to find out about the effects of a drug called mavoglurant on alcohol consumption.

NCT ID: NCT06126107 Recruiting - Alcohol Consumption Clinical Trials

Gain and Loss Framed Text Messaging to Reduce Drinking Among Older Adults

GLOSS
Start date: February 26, 2024
Phase: N/A
Study type: Interventional

The goal of this study is to evaluate effectiveness of scalable, tailored text- messaging programs for alcohol use among older adults. This study focuses on gain and loss framing of behavior change goals (i.e., the positives of change and the negatives of remaining with the status quo), critical components of behavioral science and health behavioral interventions. Loss-framing is used to motivate individuals to avoid future problems by focusing on the consequences of no change in behavior, and gain-framing is used to facilitate progress by focusing on the benefits of change. The investigators will design and evaluate three text-messaging programs using a randomized controlled trial: (A) Loss-framed messaging (B) Gain-framed messaging; and (C) Combined (loss and gain) messaging among a sample of 150 older adults with hazardous drinking. Participants will be randomized to one of the three conditions, each of which will include 8 weeks of text-messaging. During the study participants will completed assessments online and via text messages to track drinking.

NCT ID: NCT05873556 Completed - Alcohol Consumption Clinical Trials

Testing Brief Personalized Feedback Integrating Lab-based Alcohol Cue Information

Project ACE
Start date: May 8, 2023
Phase: N/A
Study type: Interventional

This study aims to develop a brief intervention that uses information from a lab-based cue reactivity protocol to create personalized feedback targeting high-risk alcohol use among young adults who drink alcohol. The intervention mainly focuses on providing feedback on individuals' drinking desire, mood, willingness to drink, and alcohol demand by comparing scores before and after viewing and smelling an alcoholic beverage in the lab session. Other psycho-educational alcohol-related content is also provided in the intervention including strategies for decreasing exposure to cues that increase drinking desires and how to cope with increased desire to drink. This brief intervention is used in a randomized controlled trial (RCT) comparing young adults who receive the brief, online intervention to those who did not receive the brief, online intervention. Participants in both groups complete baseline, lab-based cue reactivity protocol, 2-week follow-up and 3-month follow-up.

NCT ID: NCT05864235 Enrolling by invitation - Alcohol Consumption Clinical Trials

Texting to Reduce Alcohol Misuse Pilot Trial

TRAM
Start date: May 4, 2023
Phase: N/A
Study type: Interventional

The primary aims of this project are to determine the feasibility and acceptability of recruiting and retaining young adult binge drinkers online and using text messaging to provide weekly Goal Support (GS) or weekly GS + Coaching for Context-specific Peer Support (CCPS) on alcohol consumption. The secondary aims will determine effect sizes for GS and GS+CCPS groups relative to controls on alcohol consumption at 6- and 12-weeks to inform design of an adequately-powered trial.

NCT ID: NCT05767567 Completed - Alcohol Consumption Clinical Trials

Evaluating the Efficacy of a Brief Online Intervention Among Current Heavy Drinkers

Start date: March 2, 2023
Phase: N/A
Study type: Interventional

Unhealthy alcohol consumption is common in the UK and causes tremendous harm to the individual, as well as harm to others. A significant gap in providing alcohol support is that most people with unhealthy alcohol consumption will never receive advice to cut down on their drinking. However, many are interested in self-directed interventions to help them evaluate their drinking and to motivate reductions in alcohol use. One such promising intervention uses online personalised normative feedback (PNF) which compares a person's drinking with others in the general population of the same age and sex. PNF interventions are thought to work because many people with unhealthy alcohol consumption overestimate how much others drink. Multiple trials have demonstrated that providing PNF to people with unhealthy consumption reduces their alcohol use . While several UK websites do provide feedback on assessment of risk (e.g., Down Your Drink introductory section, Alcohol Change UK), there appears to be no online intervention that provides PNF for unhealthy alcohol consumption. The major objective of this pilot project is to conduct a two-arm, parallel group randomised controlled trial (RCT) in which 1,318 participants recruited from the Prolific website who have identified themselves as drinking 14 or more units per week are randomly assigned to one of two groups - a) those who are offered a PNF report, and b) those in a no intervention comparator group. Participants in the comparator group will not be provided any intervention materials but will instead be given a list of the different components of the PNF feedback and will be asked to think about how useful they would find each of them. Follow-up assessment will occur at 1 and 6 months post-randomisation. The project is described as a pilot because it is a preliminary evaluation of the PNF intervention in a UK context.

NCT ID: NCT05619406 Recruiting - Hypertension Clinical Trials

Systematic Investigation of Blacks With Stroke - GENOMICS

SIBSGENOMICS
Start date: August 20, 2022
Phase: N/A
Study type: Interventional

The overall goal of SIBS-GENOMICS is to utilize the best available contextual data on stroke in Africa to develop & validate stroke risk estimation models, translate the best model into a mobile phone app and conduct a randomized control trial of the app with a co-created motivational education video, to determine their effectiveness for improvement of stroke risk factor awareness and global risk reduction among Africans.

NCT ID: NCT05608109 Recruiting - Alcohol Consumption Clinical Trials

A Social Media Personalized Normative Feedback Intervention for Heavy Drinking College Students

SMASH
Start date: January 9, 2022
Phase: N/A
Study type: Interventional

This study seeks to evaluate the unique and synergistic efficacy of social media-specific personalized normative feedback targeting the reduction of alcohol use among heavy-drinking college students who post alcohol-related content on social media. Hypothesis: Alcohol personalized normative feedback, social media-specific personalized normative feedback, and the Alcohol personalized normative feedback+ social media-specific personalized normative feedback conditions will be more effective in reducing drinking than the attention control condition.

NCT ID: NCT05385484 Active, not recruiting - Clinical trials for Human Immunodeficiency Virus

A Savings Intervention to Reduce Men's Engagement in HIV Risk Behaviors

Start date: July 18, 2022
Phase: N/A
Study type: Interventional

This randomized control trial will test an economic intervention to reduce Kenyan men's engagement in behaviors that increase the risk of HIV/STIs. Participants randomized to the intervention group will be able to open accounts with a partner bank and will be incentivized to save with lottery-based rewards.

NCT ID: NCT05308459 Active, not recruiting - Physical Inactivity Clinical Trials

Data Health VET - Data-driven Health Promotion at Vocational Education and Training Schools

Start date: January 19, 2022
Phase: N/A
Study type: Interventional

The purpose of this study is to investigate the effectiveness of a data driven and dynamic systems approach at Danish Vocational schools to promote student health behavior and wellbeing and school organizational readiness.

NCT ID: NCT05258864 Completed - Alcohol Consumption Clinical Trials

Pilot Trial of an Online Personalised Normative Feedback Intervention to Reduce Drinking

Start date: February 27, 2022
Phase: N/A
Study type: Interventional

Unhealthy alcohol consumption is common in the UK and causes tremendous harm to the individual, as well as harm to others. A significant gap in providing alcohol support is that most people with unhealthy alcohol consumption will never receive advice to cut down on their drinking. However, many are interested in self-directed interventions to help them evaluate their drinking and to motivate reductions in alcohol use. One such promising intervention uses online personalised normative feedback (PNF) which compares a person's drinking with others in the general population of the same age and sex. PNF interventions are thought to work because many people with unhealthy alcohol consumption overestimate how much others drink. Multiple trials have demonstrated that providing PNF to people with unhealthy consumption reduces their alcohol use . While several UK websites do provide feedback on assessment of risk (e.g., Down Your Drink introductory section, Alcohol Change UK), there appears to be no online intervention that provides PNF for unhealthy alcohol consumption. The major objective of this pilot project is to conduct a two-arm, parallel group randomised controlled trial (RCT) in which 1,318 participants recruited from the Prolific website who have identified themselves as drinking 14 or more units per week are randomly assigned to one of two groups - a) those who are offered a PNF report, and b) those in a no intervention comparator group. Participants in the comparator group will not be provided any intervention materials but will instead be given a list of the different components of the PNF feedback and will be asked to think about how useful they would find each of them. Follow-up assessment will occur at 1 and 6 months post-randomisation. The project is described as a pilot because it is a preliminary evaluation of the PNF intervention in a UK context.