Brain-imaging and Adolescent Neuroscience Consortium

Alcohol Abuse Clinical Trial

— BANC  

Official title:

Brain-imaging and Adolescent Neuroscience Consortium

Clinical Trial Details — Status: Withdrawn

Administrative data

• NCT number: NCT01511679
• Other study ID #: BANC RFA-AA-12-006
• Status: Withdrawn
• Phase: N/A
• First received: January 13, 2012
• Last updated: January 2, 2013
• Start date: September 2012
• Est. completion date: September 2017

Study information

• Verified date: January 2013
• Source: Children's Hospital Boston
• Contact: n/a
• Is FDA regulated: No
• Health authority: United States: Institutional Review Board
• Study type: Observational

Clinical Trial Summary

This is a multi-site study of adolescents 12-21 years-of-age to evaluate the long and shorter-term effect of adolescent alcohol use on the developing brain.

Description:

The overall specific aims of this study are to: 1) assess the short and long-term consequences of alcohol exposure on brain, cognitive, and emotional/regulatory development during preadolescence and adolescence; 2) determine the effects of timing, dose, and duration of alcohol on brain and cognitive development; 3) assess recovery of neural and behavioral function to determine if the plasticity of the adolescent brain makes it more or less vulnerable to alcohol's acute and chronic effects; 4) understand how other key covariates (e.g., existing or emerging psychopathology, family history of alcoholism, demographics, pubertal development) factor into alcohol's effects on the brain; and 5) identify early neural, cognitive, and affective markers that may predict alcohol abuse and dependence during adolescence and/or adulthood.

Recruitment information / eligibility

• Status: Withdrawn
• Enrollment: 0
• Est. completion date: September 2017
• Est. primary completion date: March 2017
• Accepts healthy volunteers: No
• Gender: Both
• Age group: 12 Years to 21 Years

Eligibility

Inclusion Criteria:

• able to read and understand English

• available for follow-up

• parental consent/adolescent assent for those 12-17 years

• consent for those 18-21 years

Exclusion Criteria:

• Weight > 300 lbs

• braces or unremovable embedded metal

• claustrophobia or inability to lie still in MRI machine

• current or past 12-mos pregnancy (females)

• requires urgent medical/mental health care

Study Design

Observational Model: Cohort, Time Perspective: Prospective

Related Conditions & MeSH terms

• Alcohol Abuse

Locations

Country	Name	City	State
United States	McLean Hospital	Belmont	Massachusetts
United States	Boston University School of Medicine	Boston	Massachusetts
United States	Massachusetts General Hospital	Boston	Massachusetts
United States	Massachusetts Institute of Technology	Cambridge	Massachusetts

Sponsors (4)

Lead Sponsor	Collaborator
Children's Hospital Boston	Massachusetts General Hospital, Massachusetts Institute of Technology, Mclean Hospital

Country where clinical trial is conducted

United States, 

External Links

•   Center for Adolescent Substance Abuse Research at Children's Hospital Boston