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Alcohol Abuse clinical trials

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NCT ID: NCT01784627 Withdrawn - Nicotine Dependence Clinical Trials

Trial of Computerized SBI to Reduce Teen Alcohol Use

Start date: January 2015
Phase: Phase 1
Study type: Interventional

The goal of this project is to test the effectiveness of a computer-facilitated alcohol screening and brief intervention (c-ASBI) system for 12- to 18-year-old primary care patients in a multi-site, randomized comparative effectiveness trial. The investigators hypothesize that, among 12- to 18-year olds patients coming for annual well-care, those receiving c-ASBI will have lower rates of any alcohol use at 3-, 6-, and 12-month follow-ups compared to Treatment As Usual (TAU).

NCT ID: NCT01758523 Completed - Alcoholism Clinical Trials

Dutasteride Treatment for the Reduction of Heavy Drinking in Men

Start date: January 2013
Phase: Phase 4
Study type: Interventional

This study will examine the safety and potential benefit of the medication dutasteride to help men reduce or stop drinking alcohol.

NCT ID: NCT01709201 Withdrawn - Alcohol Abuse Clinical Trials

Reducing Problematic Substance Use in Youth With Chronic Medical Conditions

Start date: July 2013
Phase: N/A
Study type: Interventional

The investigators goal is to pilot a substance use-related brief intervention (BI) for youth with chronic medical conditions, obtaining preliminary evidence of feasibility, acceptability and impacts of the approach for reducing substance use among this group.

NCT ID: NCT01707030 Completed - Hepatitis C Clinical Trials

Web-based Intervention to Reduce Alcohol Use in Veterans With Hepatitis C

Start date: March 1, 2015
Phase: N/A
Study type: Interventional

Many people who are infected with Hepatitis C misuse alcohol, which is even more dangerous for them than it is for a non-infected person. In this VA study, such individuals will be screened and given feedback on their drinking using an Internet-based program which has been shown to reduce drinking in other populations. The research team will evaluate whether the program helps Veterans drink less over time and thereby improve their health.

NCT ID: NCT01678196 Active, not recruiting - PTSD Clinical Trials

Helping Families Help Veterans With PTSD and Alcohol Abuse: An RCT of VA-CRAFT

Start date: May 2013
Phase: N/A
Study type: Interventional

This project begins to evaluate the effectiveness of a web-based family outreach tool that is designed to promote treatment engagement among Veterans with posttraumatic stress disorder (PTSD) or alcohol use disorders (AUDs) but who have not yet engaged in mental health care. The National Center for PTSD has developed an on-line, Veteran-tailored, interactive web tool called VA - Community Reinforcement and Family Training (VA-CRAFT) that trains family members to effectively help their Veterans to engage in treatment for PTSD and/or AUDs. This project will provide preliminary information about VA-CRAFT's effectiveness.

NCT ID: NCT01663337 Active, not recruiting - PTSD Clinical Trials

Sequence of Symptom Change During AUD or PTSD Treatment for Comorbid PTSD/AUD

Start date: March 2013
Phase: N/A
Study type: Interventional

The broad, long-term objective of the current research is to improve treatment outcomes for individuals with comorbid posttraumatic stress disorder (PTSD) and alcohol abuse and dependence (AUD). The purpose of which is to evaluate changes in both PTSD symptoms and alcohol use and cravings associated with Cognitive Processing Therapy (CPT) or Relapse Prevention (RP) treatment in individuals with PTSD/AUD, along with mediators and moderators of outcomes. The study will randomize 235 PTSD/AUD participants recruited from the VA and from the community to CPT, RP, or Interactive Voice Response (IVR) assessment only (AO). Those in the AO condition will be re-randomized after the treatment phase to either RP or CPT. Individuals will be assessed pretreatment, immediately post-treatment, 3-, 6-, 9-, and 12-months post-treatment and will monitor symptoms daily throughout treatment.

NCT ID: NCT01643044 Completed - Alcohol Abuse Clinical Trials

Computer-delivered Screening and Brief Intervention for Alcohol Use in Pregnancy

Start date: April 2011
Phase: Phase 1
Study type: Interventional

The purpose of this study is to lay the ground work for a fully powered clinical trial of a computer-delivered screener and intervention for alcohol use during pregnancy. The pilot study will include: 1. Evaluation of the usefulness of handheld devices and anonymous screening for self report of at-risk alcohol use among pregnant women. 2. Assessing the validity of an alcohol biomarker, Ethyl Glucoronide (EtG), for the detection of at-risk drinking in pregnant women. 3. Evaluation of the efficacy of a computer-delivered brief intervention and use of tailored handouts to supplement the computer-based brief intervention focusing on alcohol use during pregnancy.

NCT ID: NCT01642381 Completed - Alcoholism Clinical Trials

Component Analysis for Motivational Interviewing

Start date: May 2012
Phase: N/A
Study type: Interventional

The purpose of this study is to investigate the critical components of motivational interviewing (MI), a psychotherapeutic intervention, in reducing heavy or problematic drinking. The study will disaggregate MI into its component parts and test full MI compared to MI without its directive strategies. This study will test whether the directive elements of MI are critical or whether MI effects may be attributable solely to its Rogerian, non-directive components. For more information, go to http://caspirnyc.org/p_motion.html

NCT ID: NCT01632319 Completed - Depression Clinical Trials

Therapy for Undergraduate College Students Who Binge Drink and Are Depressed

TREADS
Start date: May 2012
Phase: N/A
Study type: Interventional

The purpose of this study is to investigate the effectiveness of 2 different therapy courses for undergraduate college students who binge drink and experience depressive symptoms.

NCT ID: NCT01621711 Active, not recruiting - Substance Abuse Clinical Trials

Continuing Care Following Drug Abuse Treatment: Linkage With Primary Care

Linkage
Start date: March 2011
Phase: N/A
Study type: Interventional

This component of a larger Center of Research Excellence Grant improves treatment for drug abuse by developing effective linkages between specialty drug treatment and primary health care.