Clinical Trials Logo

Clinical Trial Summary

This study will evaluate the effects of inhaled fluticasone on cell counts and inflammatory mediators measured in sputum of healthy volunteers following exposure to inhaled lipopolysaccharide.


Clinical Trial Description

n/a


Study Design

Allocation: Randomized, Endpoint Classification: Pharmacodynamics Study, Intervention Model: Crossover Assignment, Masking: Double Blind (Subject, Investigator), Primary Purpose: Diagnostic


Related Conditions & MeSH terms


NCT number NCT00869596
Study type Interventional
Source Merck Sharp & Dohme Corp.
Contact
Status Completed
Phase Phase 1
Start date March 2009
Completion date September 2009

See also
  Status Clinical Trial Phase
Completed NCT00994175 - A Randomized, Placebo-Controlled, Double-Blind Pilot Study of Pioglitazone Hydrochloride in Severe, Refractory Asthma Phase 2
Not yet recruiting NCT04885738 - The Value of FeNO in Predicting Airway Eosinophilic Inflammation
Recruiting NCT02767973 - To Identify Persons Who Are Susceptible to WSP-induced Inflammation and Examine the Role of GSTM1 and Other Factors in This Susceptibility N/A
Completed NCT00814281 - Airborne Ultrafine and Fine Particulate Matter: A Cause for Endothelial Dysfunction in Man? N/A
Completed NCT03861390 - Woodsmoke Particulate + Prednisone Phase 1/Phase 2
Completed NCT00455377 - Lung Function and Airway Inflammation in Portland Cement Workers N/A
Completed NCT00527345 - Children's Exposures/Health Effects/Diesel Exhaust N/A
Completed NCT03444298 - A Study of Gamma Tocopherol-enriched Supplement on Lower Airway Responses to Inhaled Wood Smoke in Healthy Adults Phase 2
Withdrawn NCT00604578 - Pioglitazone Hydrochloride (Actos(Registered Trademark)) to Treat Asthma Phase 2
Completed NCT00989365 - Effect of Aerobic Training on Asthmatic Patients N/A
Completed NCT00673907 - HIPWOODS - Health Effects Related to Exposure to Particle Pollution From Woodburning Stoves N/A
Completed NCT00635882 - Asthma Study Comparing Anti-Inflammatory Effects of 3 Doses of Mometasone Furoate/Formoterol Fumarate and Medium Dose Mometasone Furoate (Study P05122 AM1)(COMPLETED) Phase 2
Enrolling by invitation NCT03851406 - Woodsmoke Particulate + Hypertonic Saline N/A
Completed NCT03924635 - An Exploratory Study to Characterise Changes in Airway Inflammation, Symptoms, Lung Function and Reliever Use in Adult Asthma Patients Phase 4
Completed NCT00727714 - Lung Function and Inflammatory Markers in Cement Dust Exposed Workers: A Cross-shifts Study N/A