Airway Inflammation Clinical Trial
Official title:
A Randomized Clinical Trial to Assess the Effects of Inhaled Fluticasone on Sputum Neutrophils After Low-dose Inhaled Endotoxin Challenge in Healthy Subjects
This study will evaluate the effects of inhaled fluticasone on cell counts and inflammatory mediators measured in sputum of healthy volunteers following exposure to inhaled lipopolysaccharide.
n/a
Allocation: Randomized, Endpoint Classification: Pharmacodynamics Study, Intervention Model: Crossover Assignment, Masking: Double Blind (Subject, Investigator), Primary Purpose: Diagnostic
Status | Clinical Trial | Phase | |
---|---|---|---|
Completed |
NCT00994175 -
A Randomized, Placebo-Controlled, Double-Blind Pilot Study of Pioglitazone Hydrochloride in Severe, Refractory Asthma
|
Phase 2 | |
Not yet recruiting |
NCT04885738 -
The Value of FeNO in Predicting Airway Eosinophilic Inflammation
|
||
Recruiting |
NCT02767973 -
To Identify Persons Who Are Susceptible to WSP-induced Inflammation and Examine the Role of GSTM1 and Other Factors in This Susceptibility
|
N/A | |
Completed |
NCT00814281 -
Airborne Ultrafine and Fine Particulate Matter: A Cause for Endothelial Dysfunction in Man?
|
N/A | |
Completed |
NCT03861390 -
Woodsmoke Particulate + Prednisone
|
Phase 1/Phase 2 | |
Completed |
NCT00455377 -
Lung Function and Airway Inflammation in Portland Cement Workers
|
N/A | |
Completed |
NCT00527345 -
Children's Exposures/Health Effects/Diesel Exhaust
|
N/A | |
Completed |
NCT03444298 -
A Study of Gamma Tocopherol-enriched Supplement on Lower Airway Responses to Inhaled Wood Smoke in Healthy Adults
|
Phase 2 | |
Withdrawn |
NCT00604578 -
Pioglitazone Hydrochloride (Actos(Registered Trademark)) to Treat Asthma
|
Phase 2 | |
Completed |
NCT00989365 -
Effect of Aerobic Training on Asthmatic Patients
|
N/A | |
Completed |
NCT00673907 -
HIPWOODS - Health Effects Related to Exposure to Particle Pollution From Woodburning Stoves
|
N/A | |
Completed |
NCT00635882 -
Asthma Study Comparing Anti-Inflammatory Effects of 3 Doses of Mometasone Furoate/Formoterol Fumarate and Medium Dose Mometasone Furoate (Study P05122 AM1)(COMPLETED)
|
Phase 2 | |
Enrolling by invitation |
NCT03851406 -
Woodsmoke Particulate + Hypertonic Saline
|
N/A | |
Completed |
NCT03924635 -
An Exploratory Study to Characterise Changes in Airway Inflammation, Symptoms, Lung Function and Reliever Use in Adult Asthma Patients
|
Phase 4 | |
Completed |
NCT00727714 -
Lung Function and Inflammatory Markers in Cement Dust Exposed Workers: A Cross-shifts Study
|
N/A |