Airway Extubation Clinical Trial
Official title:
Maximum Expiratory Pressure in Induced Cough as a Predictor of Extubation Failure in Intensive Care Unit Patients on Mechanical Ventilation Ready to Extubate. A Single-arm Open Clinical Trial.
Verified date | April 2020 |
Source | Hospital Nacional Profesor Alejandro Posadas |
Contact | n/a |
Is FDA regulated | No |
Health authority | |
Study type | Interventional |
Clinical trial for the evaluation of diagnostic tests. The sample was composed of adults under mechanical ventilation who passed the spontaneous breathing trial and was ready to be extubated. The maximum expiratory pressure measured in the usual way and the maximum expiratory pressure generated during the induced cough were taken as predictor variables. The outcome variable was extubation failure, measured at 72 hours and at 7 days.
Status | Completed |
Enrollment | 80 |
Est. completion date | September 9, 2019 |
Est. primary completion date | September 1, 2019 |
Accepts healthy volunteers | No |
Gender | All |
Age group | 18 Years and older |
Eligibility |
Inclusion Criteria: - Under mechanical ventilation via endotracheal tube in a period greater than 48 hours - Passing the spontaneous breathing trial an be ready for extubation. - Agree to participate in the study and sign the informed consent by the patient or family member Exclusion Criteria: - tracheostomized prior to admission to mechanical ventilation - history of neuromuscular disease - presence of unstable heart disease - received upper digestive surgery - presence of uncontained enterocutaneous fistula - candidates for non-invasive ventilation as a modality of interface exchange for extubation or as a preventive modality - patients who did not reach a MEP (habitual) of 30 cmH20 since they are not extubated by the extubation protocol of our institution. |
Country | Name | City | State |
---|---|---|---|
Argentina | Ladislao Diaz Ballve | Haedo | Buenos Aires |
Lead Sponsor | Collaborator |
---|---|
Hospital Nacional Profesor Alejandro Posadas |
Argentina,
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | Extubation failure | Endotracheal tube removal failure | 72 hours | |
Primary | Extubation failure | Endotracheal tube removal failure | 7 days |
Status | Clinical Trial | Phase | |
---|---|---|---|
Recruiting |
NCT05114551 -
ICU Predictive Score of WEaning Success in Patients At Risk of Extubation Failure
|
||
Recruiting |
NCT06154811 -
Exploring the Use of Pulse Tissue Doppler in Predicting Extubation Success in Mechanically Ventilated Patients
|
||
Recruiting |
NCT04708509 -
Extubation Advisor: Initial Implementation and Evaluation of a Novel Extubation Clinical Decision Support Tool
|
Phase 1 | |
Recruiting |
NCT06110390 -
High-flow Nasal Oxygen Therapy to Prevent Extubation Failure in Adult Trauma Intensive Care Patients
|
N/A | |
Not yet recruiting |
NCT05506904 -
Liberation From Mechanical Ventilation Using Extubation Advisor Decision Support
|
Phase 1 | |
Recruiting |
NCT05999526 -
Mechanical Ventilation Reconnection for One Hour After Spontaneous Breathing Trial
|
N/A | |
Completed |
NCT02799056 -
Diaphragmatic and Pulmonary US for Extubation Success Prediction
|
||
Not yet recruiting |
NCT04266535 -
TCI vs Manually Controlled Infusion of Propofol
|
||
Enrolling by invitation |
NCT05523479 -
The Maximizing Extubation Outcomes Through Educational and Organizational Research (METEOR) Trial
|
N/A | |
Completed |
NCT01513772 -
The Effect of Dexmedetomidine on the Emergence Agitation in Nasal Surgery
|
N/A | |
Completed |
NCT03495947 -
High Flow Nasal Cannula in Immediately Post Extubation
|
||
Recruiting |
NCT03946371 -
Relation Between the Volume of Subglottic Secretion and Risk of Extubation Failure in ICU Patients (SEGEX)
|
||
Recruiting |
NCT05356299 -
Analysis of the Magnetic Tape Bandage on Respiratory Functional Effects.
|
N/A |