Outcome
Type |
Measure |
Description |
Time frame |
Safety issue |
Primary |
Change from baseline subjective memory complaints at 6 weeks |
Measured by Memory Inventory in Chinese. The sum of score ranges from 0 to 108, higher score indicates more memory complaints. |
Six weeks after baseline |
|
Primary |
Change from baseline subjective memory complaints at 12 weeks |
Measured by Memory Inventory in Chinese. The sum of score ranges from 0 to 108, higher score indicates more memory complaints. |
12 weeks after baseline |
|
Primary |
Change from baseline subjective memory complaints at 18 weeks |
Measured by Memory Inventory in Chinese. The sum of score ranges from 0 to 108, higher score indicates more memory complaints. |
18 weeks after baseline |
|
Secondary |
Change from baseline cognitive status at 6 weeks |
Measured by the Montreal Cognitive Assessment 5-Minutes (Hong Kong Version) (HK-MoCA 5-Min) protocol. The total score ranges from 0 to 30; a higher score indicates better cognitive status. |
Six weeks after baseline |
|
Secondary |
Change from baseline cognitive status at 12 weeks |
Measured by the Montreal Cognitive Assessment 5-Minutes (Hong Kong Version) (HK-MoCA 5-Min) protocol. The total score ranges from 0 to 30; a higher score indicates better cognitive status. |
12 weeks after baseline |
|
Secondary |
Change from baseline cognitive status at 18 weeks |
Measured by the Montreal Cognitive Assessment 5-Minutes (Hong Kong Version) (HK-MoCA 5-Min) protocol. The total score ranges from 0 to 30; a higher score indicates better cognitive status. |
18 weeks after baseline |
|
Secondary |
Change from baseline working memory at 6 weeks |
Measured by Digit Span Test. The longer the series, the better the condition. |
Six weeks after baseline |
|
Secondary |
Change from baseline working memory at 12 weeks |
Measured by Digit Span Test. The longer the series, the better the condition. |
12 weeks after baseline |
|
Secondary |
Change from baseline working memory at 18 weeks |
Measured by Digit Span Test. The longer the series, the better the condition. |
18 weeks after baseline |
|
Secondary |
Change from baseline executive function at 6 weeks |
Measured by Chinese version of the Victoria Stroop Test, with more time and errors as worse condition. |
Six weeks after baseline |
|
Secondary |
Change from baseline executive function at 12 weeks |
Measured by Chinese version of the Victoria Stroop Test, with more time and errors as worse condition. |
12 weeks after baseline |
|
Secondary |
Change from baseline executive function at 18 weeks |
Measured by Chinese version of the Victoria Stroop Test, with more time and errors as worse condition. |
18 weeks after baseline |
|
Secondary |
Change from baseline lower-limb muscle strength at 6 weeks |
Measured by the 5-times chair stand task. The longer the time participants use to finish the task, the poorer the performance. |
Six weeks after baseline |
|
Secondary |
Change from baseline lower-limb muscle strength at 12 weeks |
Measured by the 5-times chair stand task. The longer the time participants use to finish the task, the poorer the performance. |
12 weeks after baseline |
|
Secondary |
Change from baseline lower-limb muscle strength at 18 weeks |
Measured by the 5-times chair stand task. The longer the time participants use to finish the task, the poorer the performance. |
18 weeks after baseline |
|
Secondary |
Change from baseline happiness at 6 weeks |
Measured by the Chinese version of the 4-item Subjective Happiness Scale. The score is the average of the four items, and ranges from 1 to 7; a higher score indicates a higher happiness level. |
Six weeks after baseline |
|
Secondary |
Change from baseline happiness at 12 weeks |
Measured by the Chinese version of the 4-item Subjective Happiness Scale. The score is the average of the four items, and ranges from 1 to 7; a higher score indicates a higher happiness level. |
12 weeks after baseline |
|
Secondary |
Change from baseline happiness at 18 weeks |
Measured by the Chinese version of the 4-item Subjective Happiness Scale. The score is the average of the four items, and ranges from 1 to 7; a higher score indicates a higher happiness level. |
18 weeks after baseline |
|
Secondary |
Change from baseline depressive symptoms at 6 weeks |
Measured by the Patient Health Questionnaire-9. The scale ranged from 0 to 27, higher score indicates higher level of depressive symptoms. |
Six weeks after baseline |
|
Secondary |
Change from baseline depressive symptoms at 12 weeks |
Measured by the Patient Health Questionnaire-9. The scale ranged from 0 to 27, higher score indicates higher level of depressive symptoms. |
12 weeks after baseline |
|
Secondary |
Change from baseline depressive symptoms at 18 weeks |
Measured by the Patient Health Questionnaire-9. The scale ranged from 0 to 27, higher score indicates higher level of depressive symptoms. |
18 weeks after baseline |
|
Secondary |
Change from baseline social isolation/integration at 6 weeks |
Measured by the Chinese version of the 6-item Lubben Social Network Scale. The total score ranges from 0 to 30; a higher score indicates a better social network. |
Six weeks after baseline |
|
Secondary |
Change from baseline social isolation/integration at 12 weeks |
Measured by the Chinese version of the 6-item Lubben Social Network Scale. The total score ranges from 0 to 30; a higher score indicates a better social network. |
12 weeks after baseline |
|
Secondary |
Change from baseline social isolation/integration at 18 weeks |
Measured by the Chinese version of the 6-item Lubben Social Network Scale. The total score ranges from 0 to 30; a higher score indicates a better social network. |
18 weeks after baseline |
|
Secondary |
Change from baseline instrumental activity of daily living at 6 weeks |
Measured by Lawton's eight selected tasks. A summary score ranges from 0 (low function, dependent) to 8 (high function, independent) for women and 0 through 5 for men to avoid potential gender bias. |
Six weeks after baseline |
|
Secondary |
Change from baseline instrumental activity of daily living at 12 weeks |
Measured by Lawton's eight selected tasks. A summary score ranges from 0 (low function, dependent) to 8 (high function, independent) for women and 0 through 5 for men to avoid potential gender bias. |
12 weeks after baseline |
|
Secondary |
Change from baseline instrumental activity of daily living at 18 weeks |
Measured by Lawton's eight selected tasks. A summary score ranges from 0 (low function, dependent) to 8 (high function, independent) for women and 0 through 5 for men to avoid potential gender bias. |
18 weeks after baseline |
|