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Aging Well clinical trials

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NCT ID: NCT06295354 Not yet recruiting - Aging Clinical Trials

Early Variations in Immune Aging

EVIA-NL
Start date: June 2024
Phase:
Study type: Observational

Background: Despite an increase in lifespan over the last decades, our healthspan lags behind. In our aging population, it is pressing that we prevent age-related morbidities and associated burden on the health care system. Instead of investigating aging in already aged populations, the currently proposed study aims to elucidate the process of immune aging in relation to biological aging, demographic and lifestyle factors in young and midlife adults, and to identify early biomarkers and pathways associated with fast versus slow immune aging and aging endotypes. Study design: A single-center, observational prospective cohort study in the Netherlands. Participants from priorly established cohorts will be invited to join the EVIA-study. We will obtain demographic and basic clinical data and biological samples (blood and stool) at baseline and after three years, with a short, yearly online questionnaire in between.

NCT ID: NCT06040554 Not yet recruiting - Aging Clinical Trials

The Effect Of A Resistance Exercise Program On Balance Of Elderly People

Start date: September 20, 2023
Phase: N/A
Study type: Interventional

The purpose of the present study is to investigate the effectiveness of a resistance exercise program consisting of elastic band exercises to balance, strength and quality of life of community-dwelling elders. The hypothesis of the study is that the people training with elastic bands will show benefits on the aforementioned areas.

NCT ID: NCT05001646 Not yet recruiting - Aging Clinical Trials

Electromagnetic Field Protection Device Use Impact in Healthy Volunteers

Start date: March 2022
Phase: Phase 2
Study type: Interventional

This is a prospective, single group, self-controlled study to evaluate the clinical and molecular impact of continuous in-home resonance-based electromagnetic field (EMF) protection device usage in healthy individuals.

NCT ID: NCT04734951 Not yet recruiting - Aging Well Clinical Trials

Muscle Quality Index Improvement by Exercise and HMB Oral Supplementation in Older Adults

Start date: June 2023
Phase: N/A
Study type: Interventional

The aging process is accompanied by a decrease in several biological and physical functions, which have an impact on the perception of well-being and quality of life. Among these, the decrease in muscle mass, strength and power are of particular importance as they are associated with poor cardiorespiratory function, functional limitations and mortality. The muscle quality index (MQI) is considered a key determinant of muscle function in adulthood. The main treatment to preserve muscle mass has been strength exercise and in some cases the use of aids that influence protein metabolism such as beta-hydroxy-beta-methyl butyrate (HMB), but the evidence on this topic is not consistent and is inconclusive. Therefore, the main purpose of this study is to investigate if the combination of a power/resistance exercise program and oral supplementation with HMB can improve the quality mass index in adults aged compared with those received a single exercise program after 14 weeks of intervention.

NCT ID: NCT04174898 Not yet recruiting - Aging Well Clinical Trials

MSC Infusion for Anti-aging and Regenerative Therapy

REGEN
Start date: April 15, 2020
Phase: Phase 1
Study type: Interventional

To evaluate the safety and efficacy of human Mesenchymal Stem Cell (hMSC) infusion therapy, in preserving general wellness and ameliorating or reversing the effects of aging in our study population