Aggressive Periodontitis Clinical Trial
Official title:
Effect of Non Surgical Periodontal Treatment on Clinical Parameters and Gingival Crevicular Fluid Il-17 and Il-18 Levels in Aggressive Periodontitis Patients
NCT number | NCT05297084 |
Other study ID # | FUE11 |
Secondary ID | |
Status | Completed |
Phase | |
First received | |
Last updated | |
Start date | March 27, 2021 |
Est. completion date | December 30, 2021 |
Verified date | March 2022 |
Source | Future University in Egypt |
Contact | n/a |
Is FDA regulated | No |
Health authority | |
Study type | Observational |
clinical parameters and IL-17 and Il-18 GCF levels were measured in 25 aggressive periodontitis patients compared to 25 periodontally healthy individuals. It was observed that that Clinical parameters and Il-17 and Il-18 levels are higher before treatment but decreased after treatment which suggests role of these interleukins in pathogenesis of aggressive periodontitis .
Status | Completed |
Enrollment | 50 |
Est. completion date | December 30, 2021 |
Est. primary completion date | December 15, 2021 |
Accepts healthy volunteers | Accepts Healthy Volunteers |
Gender | All |
Age group | 18 Years to 30 Years |
Eligibility | Inclusion Criteria: -Medically free subjects. Exclusion Criteria: - Subjects with periodontal surgeries in the last 6 months. - Subjects with prior use of antibiotics in the last 6 months. - Smokers. - Pregnant females. - Lactating females. |
Country | Name | City | State |
---|---|---|---|
Egypt | Faculty of oral and dental medicine,FUE, Cairo,Egypt | Cairo |
Lead Sponsor | Collaborator |
---|---|
Future University in Egypt |
Egypt,
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | Periopaper strips Il-17 and Il-18 GCF measurements | measurement of Il-17 and Il-18 in GCF from aggressive periodontitis patients using periopaper strips | Change from Baseline Il-17 and Il-18 at 3 months |
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