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Aggression clinical trials

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NCT ID: NCT02427672 Completed - Aggression Clinical Trials

The Effect of Prefrontal Cortex Stimulation on Antisocial and Aggressive Behavior

Start date: March 2015
Phase: N/A
Study type: Interventional

This study investigates the effect of upregulating prefrontal cortex activity on antisocial and aggressive behavior and risk factors for such behavior. In the double-blind, randomized controlled trial, participants will undergo anodal transcranial direct current stimulation bilaterally to the dorsolateral prefrontal cortex or a sham stimulation. During and after stimulation, they will complete survey and laboratory measures assessing antisocial and aggressive behavior and risk factors for antisocial and aggressive behavior. Heart rate and skin conductance will also be measured.

NCT ID: NCT02402296 Completed - Clinical trials for Localized Aggressive Periodontitis

Host Modulatory Effects of β-glucan on Localized Aggressive Periodontitis

Start date: January 2013
Phase: Phase 4
Study type: Interventional

combining the non-surgical therapy with a well-tolerated substance that can stimulate protective immune responses like B-glucan, might effectively mount resolution pathways contributing to resolving of the chronic lesion observed in aggressive forms of periodontal disease.

NCT ID: NCT02392039 Terminated - Lymphoma Clinical Trials

Study of Loratadine for Pegfilgrastim Induced Bone Pain in Patients With Aggressive Lymphoma

Start date: December 14, 2015
Phase: Early Phase 1
Study type: Interventional

The goal of this clinical research study is to learn if loratadine can control bone pain caused by pegfilgrastim (a drug given after chemotherapy to help raise white blood cell counts).

NCT ID: NCT02380703 Completed - Depression Clinical Trials

Aggression Prevention Training for Caregivers of Persons With Dementia (APT)

APT
Start date: February 5, 2015
Phase: N/A
Study type: Interventional

This study will evaluate whether a home-based targeted education and skill training (Aggression Prevention Training or APT) will reduce aggression in persons with dementia (PWD) and pain/pain-related features more than usual care plus supportive telephone calls. Half of the participants will receive APT and half will receive supportive telephone calls.

NCT ID: NCT02334098 Completed - Aggression Clinical Trials

Omega-3 Supplementation and Behavior Problems

Start date: February 2015
Phase: Phase 2/Phase 3
Study type: Interventional

The objectives of this project are as follows: 1. To assess whether omega-3 dietary supplementation for six months can reduce externalizing behavior problems (antisocial and aggressive behavior) in schoolchildren aged 8 to 18, both at the end of treatment and six months post-treatment 2. To assess whether omega-3 supplementation is more effective in children with more psychopathic-like traits.

NCT ID: NCT02327533 Completed - Clinical trials for Generalized Aggressive Periodontitis

Gene Expression Profiles in Generalized Aggressive Periodontitis: A Gene Network-based Microarray Analysis

Start date: February 2013
Phase: Early Phase 1
Study type: Observational

In this study, the investigators evaluated molecular biomarkers which play a role in the development of generalized aggressive periodontitis (GAgP) using gingival tissue samples through omics-based whole-genome transcriptomic while using healthy individuals as background controls.

NCT ID: NCT02282800 Completed - Clinical trials for Aggressive Periodontitis

Immunolocalization of 1,25,Dihydroxyvitamin D3 in Aggressive Periodontitis Patients

IVDAP
Start date: November 2010
Phase: N/A
Study type: Observational

The study was to intended to visualize the nuclear localization of vitamin D receptor in oral tissues of aggressive periodontitis patients to better understand the potential for receptor in disease activity or progression.

NCT ID: NCT02271945 Completed - Clinical trials for Relapsed/Refractory Aggressive B-cell Lymphomas

Safety/Efficacy of MEDI-551 in Combination With Immunomodulating Therapies in Subjects With Aggressive B-cell Lymphomas

Start date: December 1, 2014
Phase: Phase 1/Phase 2
Study type: Interventional

This is a Phase 1b/2 open-label study to evaluate the safety/efficacy of MEDI-551 + MEDI0680 in participants with relapsed or refractory aggressive B-cell lymphomas who have failed 1-2 prior lines of therapy.

NCT ID: NCT02242136 Completed - Clinical trials for Posttraumatic Stress Disorder

Treatment of Posttraumatic Stress Disorder and Aggressive Behavior in Soldiers and Ex-combatants

Start date: September 2014
Phase: N/A
Study type: Interventional

Soldiers deployed in peace-keeping missions as well as ex-combatants in conflict or former conflict regions were and are often exposed to multiple traumatic events and situations in which they are forced to engage in violent behavior. The treatment program Formation, Orientation and Rehabilitation by means of Narrative Exposure Therapy (FORNET) is a short-term, culturally sensitive treatment approach that aims to reduce Posttraumatic Stress Disorder (PTSD) symptoms as well as the risk to engage in uncontrolled violent behavior. Addressing trauma-related mental disorders as well as emotions related to aggression by means of FORNET is expected to facilitate reintegration in civil life and reduce uncontrolled violence. The investigators want to provide evidence, that FORNET is an effective and efficient module to assist soldiers after deployment in Somalia and/or male and female ex-combatants who fought in the civil war in Burundi. In addition the investigators aim to explore how traumatic incidences and maltreatment during childhood may influence treatment outcomes.

NCT ID: NCT02233517 Completed - Clinical trials for Posttraumatic Stress Disorder

Group CBT for Aggression in Veterans

CBT-A
Start date: February 9, 2015
Phase: N/A
Study type: Interventional

Posttraumatic stress disorder (PTSD) robustly predicts anger and aggression, and U.S. Iraq/Afghanistan-era combat Veterans report that treatment for anger and aggression is among their top priorities. PTSD-related anger and aggression are associated with profound functional impairments, yet to date there are no empirically-supported treatments for Veterans with PTSD and aggression. Effective group treatment programs could improve functioning and facilitate community reintegration for these Veterans. Given that anger impedes progress in treatment of PTSD symptoms, group anger treatment could also improve Veterans' capacity to benefit from individually-administered empirically-supported therapy for PTSD such as prolonged exposure or cognitive processing therapy.