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Aggression clinical trials

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NCT ID: NCT00627250 Completed - Clinical trials for Traumatic Brain Injury

Utility of Amantadine Hydrochloride in the Treatment of Post-traumatic Irritability

Start date: March 2003
Phase: N/A
Study type: Interventional

The purpose of this study is to determine if amantadine hydrochloride given 100 mg in the morning and at noon is safe and effective in the treatment of mood and behavior changes (i.e. irritability) after sustaining traumatic brain injury.

NCT ID: NCT00622128 Completed - Dementia Clinical Trials

Preventing Aggressive Behavior in Demented Patients

PAVeD
Start date: June 2009
Phase: Phase 3
Study type: Interventional

The purpose of this study is to develop and pilot test and non-pharmacological intervention designed to prevent the occurence of aggression in persons with dementia.

NCT ID: NCT00621751 Completed - Clinical trials for Traumatic Brain Injury

Carbamazepine for the Treatment of Chronic Post-Traumatic Brain Injury Irritability and Aggression

Start date: February 2008
Phase: N/A
Study type: Interventional

The purpose of this study is to determine if carbamazepine reduces irritability and aggression among individuals with traumatic brain injury

NCT ID: NCT00554164 Completed - Clinical trials for Lymphoma, High-grade

Positron Emission Tomography Guided Therapy of Aggressive Non-Hodgkin's Lymphomas

PETAL
Start date: November 2007
Phase: Phase 3
Study type: Interventional

The main purpose of the PETAL trial is to determine whether patients with aggressive non-Hodgkin's lymphomas with a persistently positive PET scan after two cycles of chemotherapy benefit from a change of the treatment protocol.

NCT ID: NCT00550147 Completed - Clinical trials for Attention Deficit Disorder With Hyperactivity

Quetiapine and Concerta in the Treatment for ADHD and Aggressive Behavior.

Start date: February 2004
Phase: Phase 2
Study type: Interventional

The primary purpose of this thirteen-week, open-label study is to test the hypothesis that quetiapine in combination with Oros methylphenidate will reduce aggressive symptoms in children and adolescents who have shown inadequate response to OROS methylphenidate alone.

NCT ID: NCT00521560 Completed - Clinical trials for Primary Non-Hodgkin-Lymphoma

A Study of Zevalin and Simultaneous Application of BEAM High-dose Chemotherapy Followed by Autologous Stem Cell Transplantation in Refractory and Relapsed Aggressive Non-Hodgkin Lymphomas

escZ-BEAM
Start date: March 2006
Phase: Phase 2
Study type: Interventional

Phase II Study Concomitant High-Dose Radio-Immuno- and Chemotherapy with simultaneous application of Zevalin and BEAM followed by autologous peripheral stem cell transplantation in relapsed and refractory CD 20+ Non-Hodgkin's lymphoma

NCT ID: NCT00510094 Completed - Aggression Clinical Trials

Effectiveness of Treatment for Relational Aggression in Urban African American Girls

Start date: October 2007
Phase: Phase 3
Study type: Interventional

This study will evaluate the effectiveness of a school-based social cognitive group treatment in reducing aggression (bullying) among relationally aggressive urban African American girls.

NCT ID: NCT00468130 Completed - Autism Clinical Trials

Efficacy of Aripiprazole Versus Placebo in the Reduction of Aggressive and Aberrant Behavior in Autistic Children

Abilify
Start date: May 2006
Phase: N/A
Study type: Interventional

Hypothesis: (1) Aripiprazole treatment will be superior to placebo in reducing aggression and irritability in autistic individuals as shown by reductions in the Aberrant Behavior Checklist-irritability subscale. (2) Aripiprazole treatment will be superior to placebo in the acute treatment of global autism severity. The purpose of this study is to examine the possible benefit of the medication Aripiprazole in autistic individuals.

NCT ID: NCT00467038 Completed - Clinical trials for Borderline Personality Disorder

Treatment of Aggression, Anger and Emotional Dysregulation in Borderline Personality Disorder

Start date: November 2006
Phase: N/A
Study type: Interventional

This study examines the effects of 12 months of dialectical behavior therapy (DBT) for subjects with borderline personality disorder on aggression, anger and emotional dysregulation. Treatment effects will be measured by changes in interview, self-report, psychophysiology testing and fMRI neuroimaging.

NCT ID: NCT00455234 Completed - Psychotic Disorders Clinical Trials

Rapid Tranquillization Trial: TREC-India II

TRECIndia-II
Start date: September 2005
Phase: Phase 3
Study type: Interventional

Three hundred consecutive adult patients presenting to the emergency services of the department of psychiatry and who are diagnosed by the treating doctor to be needing tranquillization to control agitated or aggressive behavior will be randomized to receive either Injection Olanzepine I.M. or Injection Haloperidol 10mg + Injection Promethazine 50 mg in this parallel group, block randomized, centrally-randomzed, allocation-concealed, assessor-blinded pragmatic clinical trial. The main outcome measure that the two treatments would be compared on would be the clinical state of the patient 4 hours after intervention, but the rate of tranquillization, degree of sedation, proportions tranquil and / or asleep at 15, 30, 60 and 240 minutes, need for additional medication, use of physical restraints, doctors called back, numbers absconding and adverse effects at each of these time points would also be compared. Compliance with oral medication and adverse effects at the end of 2 weeks would also be compared.