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Ageing clinical trials

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NCT ID: NCT01931124 Completed - Ageing Clinical Trials

High Intensity and Moderate Training and Maximal Oxygen Uptake and Activity Levels

Start date: August 2012
Phase: N/A
Study type: Interventional

Aim of the study is to investigate the effect of different types of training (high intensity and moderate training) on maximal oxygen uptake and activity levels in an elderly Norwegian population after one year training intervention. Baseline data include the activity levels assessed through self reported means as well as objectively measured activity data using activity monitors.

NCT ID: NCT01895582 Terminated - Tuberculosis Clinical Trials

Performance of IGRAs for TB Infection Diagnosis in Elderly

IGRage
Start date: July 17, 2013
Phase:
Study type: Observational

Background: Diagnosis and screening for latent tuberculosis in old patients is of special interest in regards of the morbidity-mortality of this disease in that context. TB-infection diagnosis based on immunological memory detection can be impaired with age. New blood tests (QFTB-G and T-SPOT.TB) specific for MTB infection have not been evaluated in those old patients.The primary endpoint of this study is the evaluation of the IGRAS for active TB diagnosis in patients above 75 years old.

NCT ID: NCT01857830 Completed - Stress Clinical Trials

The Relaxation vs. Retreat Study

R&R
Start date: April 2013
Phase: N/A
Study type: Interventional

The purpose of this research study is to examine whether a short term meditation intervention can improve health, mood, and biological markers of cellular stress and aging in novice and experienced meditators compared to controls.

NCT ID: NCT01765816 Completed - Ageing Clinical Trials

Generation 100: Blood Volume and Cardiac Function in Healthy Aging

Start date: August 2012
Phase: N/A
Study type: Interventional

Hypothesis: Exercise will reduce morbidity and mortality rates in an elderly population. The extent of reduction will be intensity dependent. As part of the "Generation 100" study, this sub-study project will investigate the effect of exercise on blood volume, cardiopulmonary health and heart function in healthy aging. Objective is to determine the acute effect of one endurance training session on blood volume in healthy elderly. The working hypothesis is that one interval training session increases total blood volume by 10% in healthy elderly, and that there will be no change after moderate continuous training.

NCT ID: NCT01737047 Active, not recruiting - Ageing Clinical Trials

The Effects of Ageing on the 'Pharmacokinetic and Clinical Observations in People Over Fifty'

POPPY
Start date: April 1, 2013
Phase:
Study type: Observational

The purpose of this study is to identify medical conditions that may cause particular problems to individuals receiving care for HIV infection over the age of 50. In addition, as the effects and potentially the side effects, of HIV medication may change with age, this study will also investigate the association between age and differing effects of antiretroviral therapies such as treatment outcomes, side effects and the levels of drugs in blood. Results from this study may inform future HIV treatment guidelines on how we monitor individuals with HIV infection. The results may also assist in the design of future studies for the treatment of diseases associated with ageing.

NCT ID: NCT01682330 Completed - Muscle Strength Clinical Trials

The Long-term Effects of Training on Muscle Strength and Functionality

Start date: November 2011
Phase: N/A
Study type: Observational

The purpose of the present study is to evaluate the long-term effects of 1 year of high-intensity fitness training and low-intensity whole-body vibration training on muscle strength and functionality. Therefore, muscle strength and functionality are measured after a 6-yr interval in older adults (65+).

NCT ID: NCT01666340 Active, not recruiting - Ageing Clinical Trials

Generation 100: How Exercise Affects Mortality and Morbidity in the Elderly: A Randomized Control Study

GEN100
Start date: August 21, 2012
Phase: N/A
Study type: Interventional

Hypothesis: Exercise will reduce morbidity and mortality rates in an elderly population. The extent of reduction will be intensity dependent.

NCT ID: NCT01504828 Completed - Ageing Clinical Trials

Cardiac Energetics and Function in Normal Human Ageing

Start date: July 2012
Phase: N/A
Study type: Interventional

Normal aging is characterized by altered cardiovascular function. Our preliminary data with MR imaging and spectroscopy in normal subjects without cardiovascular disease or hypertension show that age-related cardiac dysfunction is characterized initially by impaired relaxation of the heart (40 - 60 years), and then at > 60 years altered contraction and impaired myocardial energetics. For the first time, the investigators will test whether the functional and energetic effects of normal aging can be reversed by acutely reducing stiffness of peripheral blood vessels using an ACE inhibitor. This will potentially have important insights into how normal aging affects the heart, and how potential treatments could be used to attenuate this process.

NCT ID: NCT01466582 Active, not recruiting - HIV-1-infection Clinical Trials

Comorbidity and Aging With HIV

agehIV
Start date: October 2010
Phase:
Study type: Observational

In this prospective cohort study the investigators will assess the prevalence and incidence of a broad range of age-related co-morbidities and their (known) risk factor among HIV-patients and HIV-negative controls. HIV might cause premature onset or accelerated aging and could therefore result in an increase of age-related comorbidities when compared with controls.

NCT ID: NCT01451476 Completed - Ageing Clinical Trials

Human Skin Aging: Clinical Parameters and Gene Expression Profiling

GEP
Start date: May 2010
Phase:
Study type: Observational

Skin aging is a complex process involving genetic and environmental factors. The investigators hope to learn more about how human genes and their function can contribute to skin aging and human health.