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Clinical Trial Summary

The goal of this study is to assess a battery of visual function tests in subjects with non-exudative age-related macular degeneration


Clinical Trial Description

Age-related macular degeneration (AMD) is one of the leading causes of visual impairment among elderly populations in developed countries. Majority of AMD patients (80%) suffer from the dry or non-exudative form of the disease. Currently there are no approved treatments for dry AMD. Clinical development of therapeutic agents for dry AMD is limited by slow progressing nature of the disease as well as the lack of sensitive endpoints to assess therapeutic efficacy. Visual acuity, the commonly used functional endpoint, remains minimally affected during early stages of dry AMD. Thus novel visual function endpoints, that can identify functional deficits during early stages of dry AMD prior to development of geographic atrophy, are needed. In the current study a battery of visual function tests will be evaluated in subjects with different stages of dry AMD and normal controls, to assess their sensitivity and feasibility as potential functional endpoints for dry AMD. ;


Study Design


Related Conditions & MeSH terms


NCT number NCT03275753
Study type Observational
Source ORA, Inc.
Contact
Status Terminated
Phase
Start date September 21, 2017
Completion date December 31, 2022

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