Age Related Macular Degeneration Clinical Trial
Official title:
SOD as Antioxidant Treatment OF ARMD
INTRODUCTION:
Acting directly on the anti-radical enzyme chain, the superoxide dismutase (SOD), a major
enzyme of the anti-oxidant system, provides an alternative of the antioxidants treatment in
ARMD. Its synthesis depends on the cellular oxygenated reactive species, and leads to the
conversion of the superoxide ion (O2-) into hydrogen peroxide (H2O2). This compound is the
cell watch guard continuously regulating a free radicals' detoxifying chain. Subsequently,
by increasing the production of H2O2, the administration of SOD can trigger
endogenous/internal antioxidant mechanisms.
Oral administration of SOD is possible in its galenic form, Glisodine. The purpose of this
study was to evaluate the protective effect of SOD on the bilateralization of the disease.
n/a
Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Double Blind (Subject, Caregiver, Investigator, Outcomes Assessor), Primary Purpose: Prevention
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