Age Related Macular Degeneration Clinical Trial
Official title:
Macular Pigment Optical Density in Healthy Subjects
The macular pigment (MP) in humans consists of the yellow, blue-absorbing carotenoids lutein
and zeaxanthin, which are contained in vegetables and fruits. The highest concentrations of
lutein and zeaxanthin are found in the fovea. Since light entering the eye passes through
the MP before reaching the photo receptors it absorbs a significant portion of
short-wavelength light. There is evidence that these absorbing properties of the MP as well
as the ability of inactivating highly reactive oxygen species are protective for the retina.
Measurement of macular pigment is difficult and the investigators have recently proposed a
way of measuring macular pigment optical density (MPOD) based on optical reflectometry.
There is increased interest in these measurements in the recent years, because a number of
studies has provided evidence that low fruit and vegetable consumption increases the risk of
age related macular degeneration (AMD). The present study investigates MP optical density
(OD) in healthy volunteers and is used to form a database.
Furthermore the nutritional habits and the influence on MP density will be evaluated.
n/a
Observational Model: Case-Only, Time Perspective: Prospective
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