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The Effect of Dilution and Prolonged Injection Time on Dexamethasone-induced Perineal Irritation

Adverse Effect Clinical Trial

Official title:
The Effect of Dilution With Glucose and Prolonged Injection Time on Dexamethasone-induced Perineal Irritation

Clinical Trial Summary

The purpose of this study is to investigate the efficacy of dilution with glucose and prolonged injection time on dexamethasone 21-phosphate induced perineal irritation (include pian and pruritus).

Clinical Trial Description

Dexamethasone is a synthetic glucocorticoid, which may cause perineal irritation when given intravenously. The major clinical manifestations are pruritus and pain，and the incidence vary between 38%-71%. Some patients undergo spontaneous remission, while others develop into severe pain or pruritus. In clinical practice, dexamethasone is always diluted with glucose in many cases, but diluted dexamethasone in relieving dexamethasone induced perineal irritation has not been studied yet. The aim of this study was to investigate the efficacy of dilution with glucose on dexamethasone induced perineal irritation. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT04950049
Study type Interventional
Source General Hospital of Ningxia Medical University
Contact Hanxiang Ma
Phone +86-13519591508
Email mahanxiang@hotmail.com
Status Not yet recruiting
Phase N/A
Start date July 15, 2021
Completion date August 31, 2021
View Details
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