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Effects of Dexmedetomidine on OI, RI and Inflammatory Factors in Patients Undergoing Palatopalatyngoplasty.

Adverse Effect Clinical Trial

Official title:
Effects of Dexmedetomidine on Oxygenation Index, Respiratory Index and Inflammatory Factors in Patients Undergoing Palatopalatyngoplasty

Clinical Trial Summary

The purpose of this study is to investigate the efficacy of dexmedetomidine on oxygenation index, respiratory index and inflammatory factors, and to explore the protective effect of the dexmedetomidine on respiratory function in patients undergoing palatopalatyngoplasty.

Clinical Trial Description

Obstructive sleep apnea syndrome is common among people, especially among obese people, Which is characterized by periodic or complete upper airway obstruction and hypoxia during sleep. Intermittent hypoxia contributes to the lung damage by increased oxidative stress, inflammation. Some researchers suggested that dexmedetomidine can inhibit inflammatory reaction and lessen the damage of respiratory function. The aim of this study is to investigate the efficacy of dexmedetomidine on oxygenation index, respiratory index and inflammatory factors, and to explore the protective effect of the dexmedetomidine on respiratory function in patients undergoing palatopalatyngoplasty. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT03612440
Study type Interventional
Source General Hospital of Ningxia Medical University
Contact Ma Hanxiang
Phone +86-13519591508
Email mahanxiang@hotmail.com
Status Not yet recruiting
Phase N/A
Start date August 1, 2018
Completion date April 30, 2019
View Details
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